CClinicalTrials.gg
Status unknownNCT03465033Updated Mar 14, 2018

Early Physiotherapy, Mandibular Motion and Sensorial Recovery After Orthognathic Surgery

An interventional study of Early Physiotherapy in Mandibular Range of Motion, Pain and Sensorial Disturbance, sponsored by University of the Basque Country (UPV/EHU). Status unknown at 1 site in Spain. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-03-14.

Sponsored by University of the Basque Country (UPV/EHU) · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Mar 2018), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Several studies describe that the maximum mandibular opening decreases 60% -70% immediately after orthognathic surgery (OS) and other variables, including laterotrusion, movement speed and facial mimic also decrease drastically. In addition, patients frequently experience temporary or permanent sensory orofacial disturbances ranging from 9% to 76% of cases.

It has been described that scheduled early physiotherapy reduces these complications.

Read the detailed description

Before the surgical intervention (T0) the maximum interincisal oral opening measurement, laterotrusion and maximum protrusion will be recorded by digital caliber. The overbite and the overjet, length of upper lip and lower facial third will be measured. The symmetry of the upper lip in a forced smile will be determined. The measurements made at T0 will be repeated at T1 (2 weeks after surgery), T2 (5 weeks after surgery), T3 (9 weeks after surgery), T4 (12 weeks after surgery), T5 (24 weeks after surgery) and T6 (after orthodontic removal).The level of pain during the measurements of the mandibular movements will be recorded in the Visual Analogue Scale, and the self-reported area of the orofacial sensory alterations by means of a diagram and the objective area by means of the sensory discrimination test of two points will be determined. In T4, the impact of the status of the function and oral structures on daily activities will be recorded through a self-pass questionnaire based on the Oral Index Daily Performance questionnaire (OIDP-sp). In the T6 the measurement of laterotrusion, protrusion and retrusion movements measured by Gysi Gothic arch will be performed.

02

Conditions studied

  • Mandibular Range of Motion
  • Pain
  • Sensorial Disturbance

Keywords

  • Orthognathic surgery
  • Jaw rehabilitation
  • Jaw Physiotherapy
  • Pain
  • Mandibular range of motion
  • Sensorial disturbance
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • ≥18 years
  • Patients treated with orthodontics and OS for correction of dentofacial deformities.

Exclusion criteria

Exclusion Criteria:

  • Patients diagnosed with temporomandibular disorders
  • Patients diagnosed with orofacial pain
  • Patients diagnosed with orofacial sensory alterations
  • Patients not treated with orthodontics
  • Patients and who need to undergo OS interventions for the treatment of Sleep Apnea-Hypopnea Syndrome
  • Patients that present cleft palate
  • Patients that present cleft lip
  • Patients diagnosed with syndromes that affect the orofacial structures.
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Investigator, Outcomes assessor)
Enrollment
50 participants (estimated)

Study arms

  • No intervention
    Usual Care

    Patients will receive basic indications of rehabilitation consisting of daily mobilization of the jaw (perform several movements a day opening movements, laterotrusion and mouth protrusion).

  • Experimental
    Early Physiotherapy

    Other: Early Physiotherapy

Interventions

  • OtherEarly Physiotherapy

    From T1 to T2 patients will perform 3 daily repetitions of active exercises:1 5 repetitions of oral opening exercises and bilateral manual progressive stretching, protrusion and maximum lateralization of the jaw on both sides, holding each movement for 5s and a session of cryotherapy applied to the masseter, temporal and suprahyoid muscles for 120s in two 60s sessions. They will also perform 30 repetitions of exercises aimed at improving the labial seal (inflate cheeks) and the symmetry of the upper lip (broad smile). From T2 to T3 30 repetitions of the same exercises will be performed and passive progressive opening will be implemented by "clamping" Patients will also perform isometric contraction exercises in opening, closing, laterotrusion, protrusion and retrusion. Each movement will be repeated 5 times and it will remain for 5s.

05

What researchers measure

Primary outcomes

  1. Pain during mandibular movements

    The level of pain during the measurements of the mandibular movements will be registered using a Visual Analogue Scale, in which point 0 represents "no pain" and point 10 "maximum pain". Values under point 5 are considered to represent mild pain and values above point 5 severe pain

    Time frame: week 12 (T4)

  2. Maximum interincisor opening

    The maximum interincisal oral opening measurement will be recorded by digital caliber

    Time frame: week 12 (T4)

Secondary outcomes

  1. Lip symmetry

    Lip symmetry will be recorded by facial photography of the patient in broad smile

    Time frame: Before OS (T0), week 2 after surgery (T1), week 5 (T2), week 9 (T3), week 12 (T4), week 24 (T5), and after orthodontic removal: up to one year after OS (T6)

  2. Orofacial sensitivity

    Self-reported area of orofacial sensory alterations will be measured by means of a diagram and the objective area by means of the sensory discrimination test of two points.

    Time frame: Week 2 after surgery (T1), week 5 (T2), week 9 (T3), week 12 (T4), week 24 (T5), and after orthodontic removal: up to one year after OS (T6)

  3. Laterotrusion

    The oral laterotrusion measurement will be recorded by digital caliber

    Time frame: Before OS (T0), week 2 after surgery (T1), week 5 (T2), week 9 (T3), week 12 (T4), week 24 (T5), and after orthodontic removal: up to one year after OS (T6)

  4. Protrusion

    The oral protrusion measurement will be recorded by digital caliber

    Time frame: Before OS (T0), week 2 after surgery (T1), week 5 (T2), week 9 (T3), week 12 (T4), week 24 (T5), and after orthodontic removal: up to one year after OS (T6)

  5. Impact of the status of the oral function and structures on daily activities

    The impact of the status of the oral function and structures on daily activities will be recorded through a self-pass questionnaire based on the Oral Index Daily Performance questionnaire (OIDP-sp)). In the OIDP index impacts are quantified by multiplying the frequency and severity scores to obtain the performance score for each of eight dimensions (eating, speaking, cleaning teeth, working, social relation, sleeping/relaxing, smiling and emotional status). The sum of these scores is considered the total impact score. This total score is divided by the maximum possible score and multiplied by 100 to give the percentage score. This scoring system yields an intuitive oral impact score.

    Time frame: Week 12 (T4)

  6. Functional oral movements - Gysi Gothic arch

    The measurement of laterotrusion, protrusion and retrusion movements measured by Gysi Gothic arch will be performed and the functional oral movements capacity will be measured bay the total of millimeters of all movements

    Time frame: After orthodontic removal: up to one year after OS (T6)

06

Study locations

1 of 1 sites recruiting
  • Department fo Stomatology II, Faculty of Medicine and Nursery, University of the Basque Country
    Leioa, Biscay 48940, Spain
    • Rafael Martínez-Conde, MD · Contact · otpmallr@ehu.eus · 34+ 946 01 2924
    • Joana Laña, BS · Contact · joana.lana@ehu.eus · 34+ 946 01 2929
    • Rafael Martínez-Conde, MD · Principal investigator
    • Joana Laña, BS · Principal investigator
    • José Ramón Rueda, MD · Sub investigator
    • Borja Santos, MD · Sub investigator
    • Xabier Marichalar, MD · Sub investigator
    Recruiting
07

References and documents

Publications

  • Altmann EB. Myofunctional therapy and orthognathic surgery. Int J Orofacial Myology. 1987 Nov;13(3):2-12. No abstract available. PubMed 3479402 ↗
  • Bell WH, Gonyea W, Finn RA, Storum KA, Johnston C, Throckmorton GS. Muscular rehabilitation after orthognathic surgery. Oral Surg Oral Med Oral Pathol. 1983 Sep;56(3):229-35. doi: 10.1016/0030-4220(83)90001-4. PubMed 6579456 ↗
  • Bonine FL. Exercises to improve facial animation after orthognathic surgery. J Oral Maxillofac Surg. 1998 Feb;56(2):281. doi: 10.1016/s0278-2391(98)90898-9. No abstract available. PubMed 9461161 ↗
  • Dietrich EM, Griessinger N, Neukam FW, Schlittenbauer T. Consultation with a specialized pain clinic reduces pain after oral and maxillofacial surgery. J Craniomaxillofac Surg. 2017 Feb;45(2):281-289. doi: 10.1016/j.jcms.2016.12.009. Epub 2016 Dec 14. PubMed 28057402 ↗
  • Essick GK, Phillips C, Kim SH, Zuniga J. Sensory retraining following orthognathic surgery: effect on threshold measures of sensory function. J Oral Rehabil. 2009 Jun;36(6):415-26. doi: 10.1111/j.1365-2842.2009.01954.x. Epub 2009 Apr 28. PubMed 19422435 ↗
  • Gallerano G, Ruoppolo G, Silvestri A. Myofunctional and speech rehabilitation after orthodontic-surgical treatment of dento-maxillofacial dysgnathia. Prog Orthod. 2012 May;13(1):57-68. doi: 10.1016/j.pio.2011.08.002. Epub 2012 Jan 25. PubMed 22583588 ↗
  • Hong SO, Baek SH, Choi JY. Physical Therapy for Smile Improvement After Orthognathic Surgery. J Craniofac Surg. 2017 Mar;28(2):422-426. doi: 10.1097/SCS.0000000000003099. PubMed 28114219 ↗
  • Montero J, Bravo M, Albaladejo A. Validation of two complementary oral-health related quality of life indicators (OIDP and OSS 0-10 ) in two qualitatively distinct samples of the Spanish population. Health Qual Life Outcomes. 2008 Nov 18;6:101. doi: 10.1186/1477-7525-6-101. PubMed 19019208 ↗
  • Phillips C, Kim SH, Tucker M, Turvey TA. Sensory retraining: burden in daily life related to altered sensation after orthognathic surgery, a randomized clinical trial. Orthod Craniofac Res. 2010 Aug;13(3):169-78. doi: 10.1111/j.1601-6343.2010.01493.x. PubMed 20618719 ↗
  • Teng TT, Ko EW, Huang CS, Chen YR. The Effect of early physiotherapy on the recovery of mandibular function after orthognathic surgery for Class III correction: part I--jaw-motion analysis. J Craniomaxillofac Surg. 2015 Jan;43(1):131-7. doi: 10.1016/j.jcms.2014.10.025. Epub 2014 Nov 1. PubMed 25439086 ↗

Individual participant data

Plan to share: Undecided

08

Registry details

Key details

Study ID
NCT03465033
Lead sponsor
University of the Basque Country (UPV/EHU)
Responsible party
Rafael Martínez-Conde Llamosas (Principal Investigator, University of the Basque Country (UPV/EHU)) — Principal investigator
First posted
Mar 14, 2018
Start date
Mar 30, 2018 (estimated)
Primary completion
Mar 9, 2020 (estimated)
Completion
Mar 12, 2021 (estimated)
Last update
Mar 14, 2018

Study contacts

Rafael Martinez-Conde, MD
Contact
otpmallr@ehu.eus
34+ 946 01 2924
Joana Laña, BS
Contact
joana.lana@ehu.eus
34+ 946 01 2929

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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