An interventional study of Multiple breath nitrogen washout in Healthy, sponsored by Hospices Civils de Lyon. Status unknown at 1 site in France. Open to participants aged 3 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-01-27.
Sponsored by Hospices Civils de Lyon · Not applicable, Interventional, and Basic science
This study is designed to establish reference values of multiple breath nitrogen washout indexes in an healthy population of volunteers (from childhood to adulthood)
Exclusion Criteria:
Procedure: Multiple breath nitrogen washout
Lung Clearance Index (LCI) will be performed in healthy volunteers with a multiple breath nitrogen washout device.
Lung Clearance Index 2.5% (LCI 2.5%) Value
Multiple breath washout is a pulmonary function test that does not require patients' cooperation. It studies the number of lung volumes (turn-over) to clear a gaz such as nitrogen form the lungs. LCI 2,5 is most frequently reported outcome measure. It corresponds to the sum of the total expired lung volumes needed to decrease the initial gaz concretion to its 1/40th, divided by functional residual capacity. LCI can be measured in infant, preschoolers and thereafter. In order to obtain reproducible tests, three acceptable maneuvers are needed.
Time frame: hour 1
Lung Clearance Index 5% (LCI 5%) Value
Time frame: hour 1
Moment ratio M1/M0 Value
Time frame: up to 1 hour
Moment ratio M0/M2 Value
Time frame: up to 1 hour
Sacin value
assessment of distal areas function
Time frame: hour 1
Scond value
assessment of conductive areas function
Time frame: hour 1
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.
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Hospices Civils de Lyon