CClinicalTrials.gg
CompletedNCT03444909CIPTExUpdated Nov 8, 2021

Collection of Information by Tocography External

An interventional study of cardiotocograph and Toconaute in Pregnancy Related, sponsored by BioSerenity. Completed at 1 site in France. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-11-08.

Sponsored by BioSerenity · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
35
Allocation
Randomized
Ages
18 Years and older
Sex
Female
01

Study summary

The purpose of this trial is to create a comparative database, with data obtained with a new monitoring device of pregnant women,Toconaute, and two standard : a clinical cardiotocograph,and an electrophysiological signal medical device. It will allow to optimize the development of this new device.

The use of the Toconaute and/or the electrophysiological medical device will succeed to the usual monitoring of pregnant women with a cardiotocograph. It will not change their medical care.

The trial will include up to 35 pregnant women between 24 and 41 weeks of amenorrhea that requires discontinuous monitoring. It will last about 12 months, with an estimated inclusion period of 11 month.

Read the detailed description

The main objective is to compare measurements for different gestational age, between: the standard cardiotocograph with those of our device, or between the standard cardiotocograph and the Toconaute and the electrophysiological device, or between the Toconaute and the electrophysiological device.

As a second objective, we want to build a database between the cardiotocograph, the Toconaute and the electrophysiological device, to optimize the development of the Toconaute device.

The trial will include up to 35 healthy adult women pregnant between 24 and 41 weeks of amenorrhea requiring discontinuous monitoring. The trial will not change the usual medical management of women, the Toconaute device will be tested following their usual monitoring. The trial will last approximately 12 months, with an estimated inclusion period of 11 months.

In order to be able to identify possible adverse effects related to the device, women participating simultaneously in another clinical trial can not be included. A delay of 1 month minimum after participation in another clinical trial is requested.

The risks associated with the use of the Toconaute in the trial are considered low and acceptable.

Participating women will receive information from the investigator or the midwife who represents it, and will cover all the points provided for in Article L1122-1. They will be informed of the risks and their right to refuse to participate in a search or to withdraw their consent at any time without incurring any liability or prejudice. Women wishing to participate will receive the newsletter and then sign a consent. A copy of the consent will be issued to them.

As part of the test, the care of the pregnant woman is not changed, the use of the Toconaute will succeed to their usual monitoring with a cardiotocograph. The investigating physician or midwife will therefore follow the recommendations of the usual medical procedure regarding measurements performed by external cardiotocography.

02

Conditions studied

  • Pregnancy Related

Keywords

  • Monitoring
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Pregnant women adult (> 18 years) from 24 to 41 weeks of amenorrhea with or without contractions
  • Requiring an intermittent monitoring (including women parturient in pre-labour)
  • speaking and understanding well French
  • Affiliated to a social security system

Exclusion criteria

Exclusion Criteria:

  • Multiple pregnancy
  • Women requiring a continuous monitoring (in advanced labour)
  • Refusal of consent
  • Minors
  • Wounds on the stomach
  • Women under protection or person not capable of following the procedure of use (according to the judgment of the investigator)
  • Allergy known about the silver, the polyamide, the synthetic materials, a component of STIMEX gel.
  • Use of device on people who the compression of a garment tightened on the stomach could cause pains, respiratory problems or worsening of the health
  • Person equipped with a device of electric stimulation;
  • Current participation in a clinical trial or participation in a previous clinical trial including a period of not past deficiency of 1 month at the time of this clinical trial.
  • Use of the device within for a resuscitation or intensive care
  • person with a defibrillator, a stimulating one of the vagus nerve, or high-frequency surgical device.
04

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
35 participants (actual)

Study arms

  • Experimental
    cardiotocograph and Toconaute

    monitoring with cardiotocograph and next with the Toconaute of Bioserenity

    Device: cardiotocograph · Device: Toconaute

  • Experimental
    Cardiotocograph and Toconaute and Electrophysiological device

    monitoring withardiotocograph and next with Toconaute and next with the electrophysiological device

    Device: cardiotocograph · Device: Toconaute · Device: electrophysiological device (Micromed)

  • Experimental
    Cardiotocograph and electrophysiological device

    monitoring with the cardiotocograph and next with the electrophysiological device (Micromed)

    Device: cardiotocograph · Device: electrophysiological device (Micromed)

Interventions

  • Devicecardiotocograph

    Monitoring of 20 min with the cardiotocograph

  • DeviceToconaute

    Monitoring of 20 min withToconaute

  • Deviceelectrophysiological device (Micromed)

    Monitoring of 20 min with the cardiotocograph

05

What researchers measure

Primary outcomes

  1. comparison of measures from Toconaute, cardiotocograph and Micromed device

    evaluation of the quality of signal (heart rate of mother and foetus, electrocardiogramme mother and foetus, contractions)

    Time frame: 1 year

Secondary outcomes

  1. creation of a comparative database between the cardiotocograph and the toconaute and the electrophysiological device (micromed)

    databases will be created comparing data from cardiotocograph and data from toconaute and data from the electrophysiological device

    Time frame: 1 year

06

Study locations

1 site
  • Salpêtrière Hospital
    Paris, 75013, France
07

Registry details

Key details

Study ID
NCT03444909
Lead sponsor
BioSerenity
Collaborators
Pitié-Salpêtrière Hospital
Responsible party
Sponsor
First posted
Feb 26, 2018
Start date
Dec 11, 2018
Primary completion
Jul 30, 2019
Completion
Dec 11, 2019
Last update
Nov 8, 2021

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2021. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion