An interventional study of Endurance training and Endurance-strength training in Obesity, sponsored by Poznan University of Medical Sciences. Completed at 1 site in Poland. Open to female participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-02-23.
Sponsored by Poznan University of Medical Sciences · Not applicable, Interventional, and Basic science
The aim of this study was to compare the effects of three months' endurance training and three months' endurance-strength training on inflammatory markers in women with abdominal obesity.
Study patients. Written informed consent was obtained from all subjects. The study meets the standards of the Declaration of Helsinki in its revised version of 1975 and its amendments of 1983, 1989, and 1996.
Study design. The study was designed as a prospective randomized trial. Subjects were randomly divided into two groups, A and B, using a randomization list. Both groups performed three month of physical training. Group A underwent endurance training, while group B performed endurance-strength training. Aside from the training, all subjects were instructed to maintain the physical activity and diet that they had been practicing so far. At baseline and after three months of physical training, blood samples for laboratory analyses were taken, anthropometric measurements were performed for both groups.
Intervention. The exercise program lasted three months, with three sessions per week. Women in both groups participated in a total of 36 training sessions. The women in group A underwent endurance exercise on cycle ergometers (Schwinn Evolution, Schwinn Bicycle Company, Boulder, Colorado, USA). Exercise sessions consisted of a five-minute warm-up (stretching exercise) at low intensity (50%-60% of maximum heart rate), a 45-minute exercise (at 50%-80% of maximum heart rate), five minutes of cycling without a load, and five minutes of closing stretching and breathing exercise of low intensity. Group B performed endurance-strength exercise consisting of a five-minute warm-up (stretching exercises) of low intensity (50%-60% of maximum heart rate), a strength component, an endurance component, 5 minutes cycling without a load, and a 5 minutes closing stretching and breathing exercise of low intensity. The 20-minute-long strength component was performed using a neck barbell and a gymnastic ball. Directly after the strength exercise, the women took part in a 25-minute endurance exercise on cycle ergometers (Schwinn Evolution, Schwinn Bicycle Company, Boulder, Colorado, USA) at 50%-80% of maximum heart rate. Both the endurance and endurance-strength training were comparable in exercise volume; the only difference was the nature of the effort.
Exclusion Criteria:
Endurance training
Behavioral: Endurance training
Endurance-strength training
Behavioral: Endurance-strength training
The women in group A underwent endurance exercise on cycle ergometers (Schwinn Evolution, Schwinn Bicycle Company, Boulder, Colorado, USA). Exercise sessions consisted of a five-minute warm-up (stretching exercise) at low intensity (50%-60% of maximum heart rate), a 45-minute exercise (at 50%-80% of maximum heart rate), five minutes of cycling without a load, and five minutes of closing stretching and breathing exercise of low intensity.
Group B performed endurance-strength exercise consisting of a five-minute warm-up (stretching exercises) of low intensity (50%-60% of maximum heart rate), a strength component, an endurance component, 5 minutes cycling without a load, and a 5 minutes closing stretching and breathing exercise of low intensity. The 20-minute-long strength component was performed using a neck barbell and a gymnastic ball. Directly after the strength exercise, the women took part in a 25-minute endurance exercise on cycle ergometers (Schwinn Evolution, Schwinn Bicycle Company, Boulder, Colorado, USA) at 50%-80% of maximum heart rate.
C-reactive protein (CRP) at baseline
Serum concentration of C-reactive protein at baseline
Time frame: At baseline
CRP after three months of physical training
Serum concentration of C-reactive protein after three months of physical training
Time frame: after three months of physical training
tumor necrosis factor alpha (TNFα) at baseline
Serum concentration of tumor necrosis factor alpha at baseline
Time frame: at baseline
TNFα after three months of physical training
Serum concentration of tumor necrosis factor alpha after three months of physical training
Time frame: after three months of physical training
soluble receptor 2 of TNF alpha (sTNF R2) at baseline
Serum concentration of soluble receptor 2 of TNF alpha at baseline
Time frame: At baseline
sTNF R2 after three months of physical training
Serum concentration of soluble receptor 2 of TNF alpha after three months of physical training
Time frame: after three months of physical training
interleukin 6 (IL-6) at baseline
Serum concentration of interleukin 6 at baseline
Time frame: At baseline
IL-6 after three months of physical training
Serum concentration of interleukin 6 after three months of physical training
Time frame: after three months of physical training
interleukin 1 (IL-1) at baseline
Serum concentration of interleukin 1 at baseline
Time frame: At baseline
IL-1 after three months of physical training
Serum concentration of interleukin 1 after three months of physical training
Time frame: after three months of physical training
visfatin at baseline
Serum concentration of visfatin at baseline
Time frame: At baseline
visfatin after three months of physical training
Serum concentration of visfatin after three months of physical training
Time frame: after three months of physical training
Body mass at baseline
Body mass at baseline
Time frame: At baseline
Body mass after three months of physical training
Body mass after three months of physical training
Time frame: after three months of physical training
Body height at baseline
Body height at baseline
Time frame: At baseline
Body height after three months of physical training
Body height after three months of physical training
Time frame: after three months of physical training
This study is completed, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Poznan University of Medical Sciences