An interventional study of PAM and PBMT in Helicobacter Pylori Infection, sponsored by Kangdong Sacred Heart Hospital. Completed at 1 site in South Korea. Open to participants aged 19 Years to 85 Years. Per ClinicalTrials.gov, last updated 2025-09-22.
Sponsored by Kangdong Sacred Heart Hospital · Not applicable, Interventional, and Treatment
Clarithromycin-resistant H. pylori is the main cause of H. pylori eradication failure. Tailored therapy on the basis of detection of a clarithromycin resistance mutation by PCR has been studied recently, however, there have been few studies comparing treatment regimen in patient with clarithromycin-resistant H. pylori. We used sequencing-based clarithromycin resistance mutation and aimed to compare PAM (proton pump inhibitor, amoxicilline, metronidazole) regimen and PBMT (proton pump inhibitor, bismuth, metronidazole, tetracyclin) regimen in patient with clarithromycin-resistant H. pylori.
Kangdong Sacred Heart Hospital is the lead sponsor of 6 studies on the registry; 2 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
treatment with PPI, metonidazole, amoxicillin
Drug: PAM
treatment with PPI, metonidazole, bismuth, tetracyclin
Drug: PBMT
treatment with PPI, metonidazole, amoxicillin
treatment with PPI, metonidazole, bismuth, tetracyclin
H. pylori eradication rate
H. pylori eradication rate
Time frame: 14 days
Plan to share: No
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This study is completed, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.
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Kangdong Sacred Heart Hospital