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CompletedNCT03425968Updated Apr 10, 2019

Lower Extremity Alignment and Dynamic Control With Associated Injury Risk in College Athletes With Knee Hyperextension

An observational study in Knee Hyperextension, sponsored by National Yang Ming Chiao Tung University. Completed at 1 site in Taiwan. Open to participants aged 20 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-04-10.

Sponsored by National Yang Ming Chiao Tung University · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
64
Ages
20 Years and older
Sex
All
01

Study summary

Knee hyperextension, also called genu recurvatum or back knee, is commonly seen in women, people with ligamentous laxity, stroke and cerebral palsy patients. This faulty posture would result in excessive tension of the passive tissues such as anterior cruciate ligament (ACL) and posterior capsule of the knee. Subjects may also develop compensations at hip and ankle joint, as well as lower extremity malalignment. Muscles surrounding the knee could also become dysfunctional when performing functional tasks requiring stability during terminal knee extension, during which uncontrolled knee hyperextension could easily be utilized to lock the joint for stability in gait and stair climbing. In athletes, landing from a jump on an extended knee is one of the common reasons resulting in ACL injury. Little is known about the injury rate of athletes with knee hyperextension who participate in sports involving jump-landing activities.

The aim of the study is to explore if knee hyperextension is associated with poor lower extremity alignment and dynamic control and injury rate in athletes requiring jump-landing activities.

One of the study hypothesis is that athlete with knee hyperextension can find more compensatory lower extremity alignments and poor control in dynamic movement than control group.

The other hypothesis is with or without knee hyperextension, the parameter of lower extremity alignment and dynamic control can predict injury rate in jump landing athlete.

Read the detailed description

Investigators expect to recruit 100 subjects into 2 group- control group and knee hyperextension group (KH group). In knee hyperextension group, investigators will include college athletes having knee hyperextension alignment, no lower extremity injuries in past three months, and participating in jump-landing activities. Control group will match the gender, age, height, weight and sports to KH group. Inclusion criteria is the same as KH group, except the knee hyperextension angle is \<5⁰ in control group. Every subjects will receive the first time assessment and follow up by filling the injury-follow-up form every months for about four months.

At the first assessment, investigators will measure lower extremity alignments include pelvic angle in sagittal plane, hip anteversion, tibiofemoral angle, knee hyperextension angle in supine and standing position, tibial rotation angle, and navicular drop; lower extremity muscle flexibility include rectus femoris, hamstrings, gastrocnemius, soleus, iliotibial band; lower extremity muscle strength include hip, knee, muscle group; dynamic control task will record tibio-femoral acceleration, angle change ground reaction force and EMG muscle firing during vertical jump and drop jump.

02

Conditions studied

  • Knee Hyperextension

Keywords

  • Injury rate
03

Who can participate

Ages eligible
20 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

college athletes in Yang-Ming University and University of Taipei

Inclusion criteria

  • age ≥ 20 years old
  • knee hyperextension ≥ 5⁰
  • participate in jump- landing sports
  • training at least 3 days per week
  • no lower extremity injury last 3 months

Exclusion criteria

Exclusion Criteria:

  • having knee surgery before
  • In the past three months have occurred lower extremity musculoskeletal injury leading the person can't participate in training or competition for at least three days
04

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
64 participants (actual)
Patient registry
No

Groups and cohorts

  • Knee hyperextension group

    athletes who has knee hyperextension

  • Control group

    athletes who doesn't have knee hyperextension

05

What researchers measure

Primary outcomes

  1. Injury type

    Record injury type

    Time frame: 4 months

  2. Injury duration

    time loss during the game or training (days)

    Time frame: 4 months

Secondary outcomes

  1. Lower extremity alignments-pelvic tilt on sagittal plane

    pelvic tilt on sagittal plane in degree

    Time frame: 1st day

  2. Lower extremity alignments-hip anteversion

    hip anteversion in degree

    Time frame: 1st day

  3. Lower extremity alignments-tibiofemoral angle

    tibiofemoral angle in degree

    Time frame: 1st day

  4. Lower extremity alignments-knee hyperextension angle

    knee hyperextension angle in supine and standing posture in degree

    Time frame: 1st day

  5. Lower extremity alignments-tibial rotation angle

    tibial rotation angle in degree

    Time frame: 1st day

  6. Lower extremity alignments-hip external rotation angle

    hip external rotation angle in degree

    Time frame: 1st day

  7. Lower extremity alignments-hip internal rotation angle

    hip internal rotation angle in degree

    Time frame: 1st day

  8. Lower extremity alignments-navicular drop

    navicular drop normalized with foot length in %

    Time frame: 1st day

  9. Rectus femoris flexibility

    measure knee angle in prone knee bend position

    Time frame: 1st day

  10. Hamstrings flexibility

    measure knee angle in 90-90 straight leg raise test

    Time frame: 1st day

  11. Gastrocnemius flexibility

    measure ankle dorsiflexion angle in standing position without rearfoot lift off the floor

    Time frame: 1st day

  12. Soleus flexibility

    measure ankle dorsiflexion angle in knee flex standing position without rearfoot lift off the floor

    Time frame: 1st day

  13. Iliotibial band flexibility

    use Ober's test to measure the angle below horizontal level

    Time frame: 1st day

  14. Dynamic task parameters-acceleration and angle

    anteroposterior acceleration and angle changes at knee joint

    Time frame: 1st day

  15. Dynamic task parameters-ground reaction force

    ground reaction force

    Time frame: 1st day

  16. Dynamic task parameters-Electromyography (EMG)

    use EMG to detect muscle firing during jump task

    Time frame: 1st day

  17. knee extensors muscle strength

    knee extensors by hand held dynamometer

    Time frame: 1st day

  18. knee flexors muscle strength

    knee flexors by hand held dynamometer

    Time frame: 1st day

06

Study locations

1 site
  • National Yng Ming University
    Taipei City, 北投區 112, Taiwan
07

Registry details

Key details

Study ID
NCT03425968
Lead sponsor
National Yang Ming Chiao Tung University
Responsible party
Sponsor
First posted
Feb 8, 2018
Start date
Feb 27, 2018
Primary completion
Aug 30, 2018
Completion
Dec 31, 2018
Last update
Apr 10, 2019

Study contacts

Wen-Yin Chen, PhD
principal investigator · National Yang-Ming University The Department of Physical Therapy and Assistive Technology

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
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