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CompletedNCT03417869QuickVue FluUpdated Mar 20, 2018

QuickVue Influenza A + B Test Field Study

An observational study in Influenza A, Influenza B, sponsored by Quidel Corporation. Completed at 5 sites in United States. Per ClinicalTrials.gov, last updated 2018-03-20.

Sponsored by Quidel Corporation · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
1,381
Sex
All
01

Study summary

Demonstrate improved clinical performance of visually read QuickVue Influenza A+B test.

Read the detailed description

The objective of this study is to demonstrate an improved clinical performance of the visually read QuickVue Influenza A+B test with nasal and nasopharyngeal swab specimens. Clinical performance will be based on comparison of QuickVue results to either cell culture or an FDA-cleared molecular test at one or more Reference Laboratories.

02

Conditions studied

  • Influenza A, Influenza B

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03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Subjects will be recruited from the general population as they present to the clinical facility. Subjects must have had a fever within the last two days and exhibiting one or more symptoms characteristic of influenza

Inclusion criteria

Subjects will be recruited from the general population as they present to the clinical facility. Subjects must have had a fever within the last two days and exhibiting one or more symptoms characteristic of influenza. They must meet the following criteria to be eligible for enrollment:

  1. Male or Female of all ages (with appropriate consent).
  2. The subject must have had of a fever, ≥ 37.8º C (100º F), within the last two days.
  3. Must also be currently exhibiting one or more of the following symptoms characteristic of influenza-like-illness (ILI).

    1. Nasal congestion
    2. Rhinorrhea
    3. Sore throat
    4. Cough
    5. Headache
    6. Myalgia
    7. Malaise

Exclusion criteria

Exclusion Criteria:

    1. Has undergone treatment with anti-influenza antivirals within the previous 7 days, to include but not be limited to, Amantadine, Rimantadine, Ribavirin, Oseltamivir, Zanamivir or any other antiviral currently available in these classes.

      1. Has been vaccinated by means of an influenza nasal spray/mist vaccine within the previous 7 days.
      1. Unable to understand and consent to participation; for minors this includes parent or legal guardian.
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Study design

Observational model
Other
Time perspective
Prospective
Enrollment
1,381 participants (actual)
Patient registry
No

Interventions

  • DeviceQuickVue Influenza A+B

    Rapid diagnostic test with IVD, QuickVue Influenza A+B

05

What researchers measure

Primary outcomes

  1. Influenza Diagnostic test result

    rapid IVD test

    Time frame: 10 minutes

06

Study locations

5 sites
  • Alliance Urgent Care
    Phoenix, Arizona 85353, United States
  • Twelve Corners Pediatrics
    Rochester, New York 14618, United States
  • Veritas, P.A.
    Belton, Texas 76513, United States
  • City Doc Urgent Care
    Dallas, Texas 75209, United States
  • Advanced Pediatrics
    Vienna, Virginia 22180, United States
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03417869
Lead sponsor
Quidel Corporation
Responsible party
Sponsor
First posted
Jan 31, 2018
Start date
Feb 16, 2017
Primary completion
Feb 1, 2018
Completion
Feb 1, 2018
Last update
Mar 20, 2018

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2018. You cannot join it, but the record below documents what was studied.

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