An interventional study of DEXA (= Dual-energy x-ray absorptiometry) in Morbid Obesity, sponsored by University Hospital, Basel, Switzerland. Completed at 1 site in Switzerland. Per ClinicalTrials.gov, last updated 2019-08-13.
Sponsored by University Hospital, Basel, Switzerland · Not applicable, Interventional, and Diagnostic
The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on bone mineral density, fracture risk, and body composition ≥ 5 years post-surgery.
Bariatric surgery shows impressive results in terms of weight loss and resolution of comorbidities. Still, there are questions as to the frequency of long-term adverse effects: data on alterations in bone health are missing,
The goal of this trial is to examine long-term effects of laparoscopic gastric bypass (LRYGB) and sleeve gastrectomy (LSG) on bone mineral density, fracture risk, and body composition ≥ 5 years post-surgery.
Exclusion Criteria:
Patients ≥ 5 years after laparoscopic gastric bypass receive DEXA (= Dual-energy x-ray absorptiometry) in order to measure bone mass density
Diagnostic Test: DEXA (= Dual-energy x-ray absorptiometry)
Patients ≥ 5 years after laparoscopic sleeve gastrectomy receive DEXA (= Dual-energy x-ray absorptiometry) in order to measure bone mass density
Diagnostic Test: DEXA (= Dual-energy x-ray absorptiometry)
measurement of vertebral bone and hip bone mineral density
Total hip T-Score measured with dual-energy x-ray absorptiometry
measured score will be compared to reference score for this age
Time frame: 5-7 years after bariatric surgery
Total vertebral T-Score measured with dual-energy x-ray absorptiometry
measured score will be compared to reference score for this age
Time frame: 5-7 years after bariatric surgery
fracture risk assessed by FRAX score
measured score will be compared to reference score for this age
Time frame: 5-7 years after bariatric surgery
plasma concentration of C-terminal telopeptide (CTX)
measured plasma concentration will be compared to reference for this age
Time frame: 5-7 years after bariatric surgery
plasma concentration of vitamin D3
measured plasma concentration will be compared to reference for this age
Time frame: 5-7 years after bariatric surgery
Plan to share: No
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This study is completed, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.
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University Hospital, Basel, Switzerland