An interventional study of Exercise + Placebo group and Exercise + Protein group in Dynapenia, Aging and Physical Impairment, sponsored by Université du Québec a Montréal. Completed. Open to male participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-01-08.
Sponsored by Université du Québec a Montréal · Not applicable, Interventional, and Prevention
Investigate the effect of 12 weeks mixed power training (power and functional exercises) combined with a protein supplementation (30g/d) or not (placebo) on physiological characteristics of muscle and functional capacities in elderly men.
Life habits are know to be able to prevent the loss of functional capacities and muscle function during aging process. More specifically, protein intake is important to maintain muscle function in older adults. Another non pharmacological intervention and well recognized for its efficacy, it's exercise training.
Recently, it has been observed than muscle quality is more important to maintain physical autonomy than muscle mass per se. In addition, muscle quality is more related to functional capacities than muscle mass.
Due to this recent finding, it has been proposed that muscle power training would be the best exercise intervention to prevent the loss of mobility.
9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.
This study's enrollment of 100 is above the median of 60 across 8,388 interventional studies indexed under Motor Activity.
Browse Motor Activity studies →Université du Québec a Montréal is the lead sponsor of 19 studies on the registry; 3 are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
50 subjects will receive a placebo supplementation with an exercise intervention (EX group)
Other: Exercise + Placebo group
50 subjects will receive a protein supplementation combined with an exercise intervention (PROTEX group)
Other: Exercise + Protein group
1/2 of the subject will follow a mixed power training: 4 power exercises + 6 functional exercises combined to a placebo
1/2 of the subject will receive 30 g/ d of protein (leucine+ vitD; divided in three equal doses: morning, afternoon and evening) + will follow a mixed power training: 4 power exercises + 6 functional exercises.
Change in walking speed
evaluate using the 4m- normal walking speed (m/sec)
Time frame: Change from Baseline walking speed at 12 weeks measure in all subjects
Change in lower limb muscle quality
Knee extension muscle strength (isometric (N)/ lower limb muscle mass (kg))
Time frame: Change from Baseline lower limb muscle quality at 12 weeks measure in all subjects
Change in mitochondrial activity
citrate synthase activity (unit: percent)
Time frame: Change from Baseline mitochondrial activity at 12 weeks measure in half of the subjects
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
The record gives a start of Sep 2013, a primary completion of Dec 2015 and a completion of Dec 2015. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Jan 2018. You cannot join it, but the record below documents what was studied.
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Université du Québec a Montréal