An observational study in Embolism, Pulmonary, sponsored by Centre Hospitalier Universitaire de Saint Etienne. Withdrawn. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-04-04.
Sponsored by Centre Hospitalier Universitaire de Saint Etienne · Observational
Among 10 studies in Pulmonary Embolism by Centre Hospitalier Universitaire de Saint Etienne — 3 open to participants now, 3 under way, 1 of them phase 3. Pulmonary Embolism · Centre Hospitalier Universitaire de Saint Etienne.
Among the 10 studies in Pulmonary Embolism by Centre Hospitalier Universitaire de Saint Etienne, this one is the only one that started in 2018, is one of 4 observational ones, and was the 5th registered.
832 studies on the registry are indexed under Pulmonary Embolism; 171 are open to participants now.
Browse Pulmonary Embolism studies →3 of the 10 studies in Pulmonary Embolism by Centre Hospitalier Universitaire de Saint Etienne are open now, in 1 country. Each count lists the studies.
Of the 129 Pulmonary Embolism studies recruiting now, 109 (84%) set no upper age limit and 5 (4%) stop at 75 or younger; 9 take children under 18; 9 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →10 studies; the count open now beside each. This study's row is marked.
First in 2006; this study’s year is marked. 1 started in 2018.
Median enrollment 306 across the 4 interventional studies, 103 across the 6 observational. Of the 6 that completed or were terminated, 0 (0%) have results posted.
Centre Hospitalier Universitaire de Saint Etienne is the lead sponsor of 597 studies on the registry; 127 are open to participants now.
1 of the studies in Pulmonary Embolism by Centre Hospitalier Universitaire de Saint Etienne that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06386107Centre Hospitalier Universitaire de Saint EtienneThrombin Generation Parameters and Bleeding in Patients Treated With Anticoagulants for Cancer Associated Thrombosis | 2027-07 |
Among the 10 studies in Pulmonary Embolism by Centre Hospitalier Universitaire de Saint Etienne, from their registry updates:
Nothing recorded among them since 2026-09-25.
Pulmonary Embolism (PE) is a frequent disease, the third cause of cardiovascular death after stroke and myocardial infarction. According to European guidelines of European Society of Cardiology (ESC) and of European Respiratory Society (ERS), the prognostic stratification of PE severity is mandatory as soon as PE is diagnosed. This stratification includes the hemodynamic status, and specific tools : the assessment of the sPESI score, and the evaluation of PE's impact on right ventricle (RV) : increased biomarkers (troponin, BNP) and right ventricle/left ventricle (RV/LV) ratio.
the RV/LV ration may be evaluated ideally by transthoracic echo (TTE), or by CT scan. Unfortunately, only 10% of patients with PE are evaluated with TTE by a cardiologist in the initial time of PE diagnosis. Hence, the CT scan is the most frequent way to assess RV/LV ratio. However, CT is not possible for all patients (patients with contra-indication) or may have difficulties to provide a clear assessment because of technical issues.
Then, there is a need for morphological evaluation of RV as soon as PE is diagnosed, in every clinical setting. The improvement in technologies allowed the development of clinical echography (CE) in emergency departments.
CE is already available, non-invasive, less expansive, and may be a good way to assess RV/LV ratio in patients with PE diagnosed in emergency departments.
The investigators propose a prospective, multicenter study to assess the sensitivity of CE in patients with PE, compared to CT scan to detect RV/LV ≥0.9.
All patients with a PE confirmed in emergency unit
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
patients with pulmonary embolism confirmed by tomography scan in emergency department
Procedure: clinical echography (CE)
clinical echography (CE) is performed in the first 24 hours following the diagnosis of PE, in emergency unit
Patients with a measure RV/LV ratio ≥ 0.9 on clinical echography (CE) and CT Scan
Sensitivity of clinical echography (CE) to CT Scan to detect an increased RV/LV ratio above 0.9.
Time frame: day 1
Patients with a measure RV/LV ratio < 0.9 on clinical echography (CE) and CT Scan
Specificity of clinical echography (CE) to CT Scan to detect an increased RV/LV ratio below 0.9
Time frame: day 1
Patients with abnormal inferior vena cava.
Time frame: day 30
death
Time frame: day 30
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is withdrawn, as verified in Mar 2019. You cannot join it, but the record below documents what was studied.
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