An observational study in Obesity and Physical Fitness, sponsored by Louis Pérusse. Completed. Open to participants aged 10 Years and older. Per ClinicalTrials.gov, last updated 2017-11-28.
Sponsored by Louis Pérusse · Observational
The Quebec Family Study (QFS) is an observational study that was planned to investigate the role of genetic factors in physical fitness, body composition, risk factors for common disease and health-related behaviour.
The Quebec Family Study was an observational study with three cycles of data collection between 1978 and 1992. During the first cycle of data collection (Phase 1: 1978-1982), a total of 1,650 subjects from 375 families were recruited. During the second cycle (Phase 2: 1989-1997), 385 subjects from 105 phase 1 families were retested and an additional 372 subject from 74 families were recruited. During the third cycle (Phase 3: 1998-2002), 204 subjects from phase 1 were tested a third time, 113 subjects from phase 2 were tested a second time and 194 new subjects from 44 families were recruited.
The QFS cohort is a mixture of random sampling and ascertainment through obese individuals. In Phase 1 of the study, subjects were randomly selected from French-Canadian families living in the Quebec city area, In Phases 2 and 3 of the study, families with a least one obese parent and one obese offspring were recruited.
Exclusion Criteria:
Body composition
Body composition as assessed by underwater weighing
Time frame: Through study completion, an average of 24 years
Body mass index (kg/m^2)
Body mass index assessed from height and weight
Time frame: Through study completion, an average of 24 years
Abdominal fat
Abdominal fat as assessed by commuted tomography
Time frame: Through study completion, an average of 24 years
Waist and hip circumferences (cm)
Waist and hip circumferences (cm)
Time frame: Through study completion, an average of 24 years
Caloric intake
Total caloric intake and macronutrient intake using a 3-day dietary record
Time frame: Through study completion, an average of 24 years
Eating behaviour
Eating behaviour assessed using the Three-Factor Eating questionnaire
Time frame: Through study completion, an average of 24 years
Energy expenditure
Oxygen consumption at rest and during exercise
Time frame: Through study completion, an average of 24 years
Physical activity level
Physical activity level assessed by questionnaire
Time frame: Through study completion, an average of 24 years
Blood pressure (mm Hg)
Systolic and diastolic blood pressure
Time frame: Through study completion, an average of 24 years
Plasma lipid levels (mmol/L)
Fasting levels of triglycerides, LDL-cholesterol and HDL-cholesterol in mmo/L
Time frame: Through study completion, an average of 24 years
Glucose levels (mmol/L)
Plasma glucose levels in a fasting state and following an oral glucose tolerance test, inflammatory markers. Plasma glucose levels in a fasting state and during an oral glucose tolerance test
Time frame: Through study completion, an average of 24 years
Insulin levels (pmol/L)
Plasma insulin levels in a fasting state and following an oral glucose tolerance test.
Time frame: Through study completion, an average of 24 years
C-reactive protein (CRP in mg/ml)
C-reactive protein (CRP in mg/ml)
Time frame: Through study completion, an average of 24 years
Adiponectin levels (in micrograms/ml)
Adiponectin levels (in micrograms/ml)
Time frame: Through study completion, an average of 24 years
Interleukin-6 (IL6) and tumor necrosis factor-alpha (TNF-alpha) in pg/ml
Interleukin-6 (IL6) and tumor necrosis factor-alpha (TNF-alpha) in pg/ml
Time frame: Through study completion, an average of 24 years
Smoking habits (nb of cigarettes per day)
Smoking habits (nb of cigarettes per day)
Time frame: Through study completion, an average of 24 years
Sleeping (hours/day)
Sleeping (hours/day)
Time frame: Through study completion, an average of 24 years
Alcohol consumption
Alcohol consumption (nb of drinks per week)
Time frame: Through study completion, an average of 24 years
No study locations are listed for this record.
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