An observational study in SCI - Spinal Cord Injury and Cardiovascular Risk Factor, sponsored by Paracelsus Medical University. Completed at 2 sites in Austria. Open to participants aged 18 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-01-29.
Sponsored by Paracelsus Medical University · Observational
The present study will analyze if exercise is able to elicit the well-known anti-atherogenic effects in patients with SCI. This will be evaluated by measuring vascular parameters such as endothelial and inflammatory blood markers, echocardiography of the heart and peripheral vessels, as well as blood pressure and arterial stiffness, in subjects performing either wheelchair dancing, wheelchair marathon or no sports. Further, it will be investigated, whether there is an association between neuroplasticity and cardiovascular health, as measured by electroencephalography (EEG), transcranial magnetic stimulation (TMS) and blood levels of the brain-derived neurotrophic factor (BDNF).
We hypothesize that the cardiovascular, physical and psychological benefits of wheelchair dancing and/or wheelchair marathon parallel improved neuroplasticity in SCI-patients
healthy participants, wheelchair users
wheelchair users independent of the cause of the walking impairment, preferably with spinal cord injury.
Exclusion Criteria:
metallic implanters, additional neurologic pathologies, pregnancy
healthy walking control participants
wheelchair users, who are performing wheelchair dancing
wheelchair users, who are participants in wheelchair/ handbike Marathon competitions
wheelchair users, who conduct exercise bouts less than 2 times per month
comparison of cardiovascular risk factors between different study groups
measurement for arterial stiffness parameters, via pulse wave analysis. Comparison between healthy individuals and patients using wheelchairs (three different groups).
Time frame: October 2017- June 2018
Evaluation of echocardiography results between different study groups
Evaluation of echocardiography comparing healthy individuals and patients using wheelchairs (three different groups).
Time frame: October 2017- June 2018
This study is completed, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.
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Paracelsus Medical University