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CompletedNCT03351595Updated Sep 21, 2026

Ewha Birth and Growth Study (Birth Cohort)

An observational study in Pediatric Health, Growth & Development and Cardiometabolic Health, sponsored by Ewha Womans University. Completed at 1 site in South Korea. Per ClinicalTrials.gov, last updated 2026-09-21.

Sponsored by Ewha Womans University · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
940
Sex
All
01

Study summary

The Ewha Birth and Growth Study is a prospective birth cohort established at Ewha Womans University Mokdong Hospital in Seoul, Republic of Korea. Pregnant women were recruited between 2001 and 2006, and their offspring were followed longitudinally from birth through childhood, adolescence, and young adulthood.

Read the detailed description

The cohort was composed of mothers who received prenatal care between 24 and 28 weeks of gestation and were recruited between 2001 and 2006. After delivery, information on birth outcomes was collected, and mail surveys were conducted when the offspring were 6, 12, 18, and 24 months of age.

Regular follow-up examinations were conducted at 3 and 5 years of age, annually from 7 through 12 years of age, and once during adolescence at 13 to 15 years of age. Follow-up examinations continued into young adulthood, with an examination at 19 years of age.

During follow-up examinations, after an 8-hour overnight fast, blood samples (3 mL EDTA blood and 5 mL serum) were obtained from participants by venipuncture, and urine samples were collected. Assessments included physical growth, blood pressure, metabolic biomarkers, dietary intake, psychological and behavioral measures, socioeconomic status, physical activity, and other health-related factors.

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Conditions studied

  • Pediatric Health
  • Growth & Development
  • Cardiometabolic Health

Keywords

  • Growth pattern
  • Environmental and prenatal exposure
  • Birth cohort
  • Longitudinal study
  • Life-course approach
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In context

Lead sponsor

Ewha Womans University is the lead sponsor of 41 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Pregnant women recruited during prenatal care and their offspring followed longitudinally from birth through young adulthood.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Pregnant women who received prenatal care between 24 and 28 weeks of gestation and were enrolled between 2001 and 2006.
  • Individuals who could participate in scheduled follow-up examinations and comply with the study requirements.

Exclusion criteria

Exclusion Criteria:

- Individuals considered unable to participate in the study procedures for other reasons, based on the investigator's judgement.

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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
940 participants (actual)
Patient registry
No
Biospecimen retention
Samples with dna
06

What researchers measure

Primary outcomes

  1. Physical growth assessed by anthropometric measurements

    Anthropometric measurements were obtained during scheduled follow-up examinations to assess longitudinal physical growth. Participants received individualized health examination results following the assessments.

    Time frame: At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age

Secondary outcomes

  1. Blood pressure assessed during follow-up examinations

    Systolic and diastolic blood pressure were measured during scheduled follow-up examinations.

    Time frame: At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age

  2. Metabolic biomarkers assessed during follow-up examinations

    Fasting blood samples were collected during scheduled follow-up examinations to assess metabolic biomarkers, including total cholesterol, HDL cholesterol, triglycerides, glucose, uric acid, and other metabolic biomarkers.

    Time frame: At 3 and 5 years of age; annually from 7 through 12 years of age; at 13 to 15 years of age; and at 19 years of age

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Study locations

1 site
  • Ewha Womans University Seoul Hospital
    Seoul, South Korea
08

References and documents

Publications

  • Lee HA, Park B, Min J, Choi EJ, Kim UJ, Park HJ, Park EA, Cho SJ, Kim HS, Lee H, Kim YJ, Hong YS, Kim EJ, Ha EH, Park H. Cohort profile: the Ewha Birth and Growth Study. Epidemiol Health. 2021;43:e2021016. doi: 10.4178/epih.e2021016. Epub 2021 Feb 22. PubMed 33677859 ↗

Individual participant data

Plan to share: Undecided

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 21, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03351595
Lead sponsor
Ewha Womans University
Collaborators
National Research Foundation of Korea
Responsible party
Sponsor
First posted
Nov 24, 2017
Start date
Sep 2001
Primary completion
Aug 2026
Completion
Aug 2026
Last update
Sep 21, 2026

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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