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CompletedNCT03348436Updated Mar 18, 2020

Study on Left Atrial Function of Paroxysmal Supraventricular Tachycardia After Radiofrequency Ablation

An interventional study of radiofrequency ablation in Paroxysmal Supraventricular Tachycardia, sponsored by Ruiqin xie. Completed at 1 site in China. Open to participants aged 14 Years and older. Per ClinicalTrials.gov, last updated 2020-03-18.

Sponsored by Ruiqin xie · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
100
Allocation
Randomized
Ages
14 Years and older
Sex
All
01

Study summary

This study to investigate the effects of RF ablation on left atrial systolic function in patients with atrioventricular nodal reentrant tachycardia (AVNRT) and atrioventricular tachycardia (AVRT).

Read the detailed description

A total of 100 patients with persistent,in whom successful RF ablation of slow pathway or accessory pathway was performed. Patients with atrial fibrillation, structural heart disease, ventricular arrhythmias, impaired left ventricular systolic function or on antiarrhythmics were excluded. All the patients had echocardiographic study before ablation 、1 day and 1 months after ablation. Left atrial systolic function was assessed using atrial ejection force (AEF) according to Manning's formula (AEF = 0.5 x ρ x MA x A(2), r: blood density = 1.06 g/cm(3), MA: mitral orifice area [cm(2)], A: A wave velocity). The following left atrial dimensions were assessed: antero-posterior (LA-AP), infero-superior (LA-IS, long axis), medio-lateral (LA-ML, short axis). The correlations between AEF and electrophysiological parameters were analysed (VA - ventriculo-atrial conduction, VA/CL - tachycardia cycle length).

02

Conditions studied

  • Paroxysmal Supraventricular Tachycardia

Keywords

  • paroxysmal supraventricular tachycardia
  • Left Atrial Function
03

Who can participate

Ages eligible
14 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

Patients with paroxysmal supraventricular tachycardia,includes atrioventricular reentrant tachycardia and atrioventricular nodal reentrant tachycardia, Age is >14 years

Exclusion criteria

Exclusion Criteria:

Atrial fibrillation, Atrial tachycardia, Structural heart disease, Ventricular arrhythmias, Patients with impaired left ventricular systolic function or on antiarrhythmics

04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
100 participants (actual)

Study arms

  • Experimental
    patients with atrioventricular nodal reentrant tachycardia

    radiofrequency catheter ablation therapy

    Procedure: radiofrequency ablation

  • Experimental
    patients with atrioventricular tachycardia

    radiofrequency catheter ablation therapy

    Procedure: radiofrequency ablation

Interventions

  • Procedureradiofrequency ablation
05

What researchers measure

Primary outcomes

  1. Left Atrial Function of postoperative radiofrequency ablation.

    Time frame: 1 month

06

Study locations

1 site
  • The Second Hospital of Hebei Medical University
    Shijiazhuang, Hebei 050000, China
07

Registry details

Key details

Study ID
NCT03348436
Lead sponsor
Ruiqin xie
Responsible party
Ruiqin xie (director of cardiology department, The Second Hospital of Hebei Medical University) — Sponsor-investigator
First posted
Nov 20, 2017
Start date
Jan 1, 2017
Primary completion
Mar 1, 2020
Completion
Mar 1, 2020
Last update
Mar 18, 2020

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.

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