ClinicalTrials.gg
CompletedNCT03299348Updated Jun 19, 2025

AgingPLUS: Promoting Physical Activity in Adults

An interventional study of AgingPLUS and Active Control Group in Physical Activity, sponsored by Colorado State University. Completed at 1 site in United States. Open to participants aged 45 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-06-19.

Sponsored by Colorado State University · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
402
Allocation
Randomized
Ages
45 Years to 75 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 17 studies in Motor Activity by Colorado State University — 4 open to participants now, 5 under way, none of them phase 3. Motor Activity · Colorado State University.

Enrollment
2nd of 17
402 · median 40
Started
2018
the only one that year
No phase
13 of 17
4 open now
Registered
6th of 17
by date

Among the 17 studies in Motor Activity by Colorado State University, this one is the 2nd largest by enrollment, is the only one that started in 2018, is one of 13 with no phase, and was the 6th registered.

Motor Activity

9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.

Browse Motor Activity studies →

Open to participants now

4 of the 17 studies in Motor Activity by Colorado State University are open now, in 1 country. Recruiting first, the newest first:

By country, each count listing its studies:

All 4 open studies →

Where they have run

Who these studies take

Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.

This study: 45 Years to 75 Years · all sexes · healthy volunteers too.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 17 studies in Motor Activity by Colorado State University, or all of them as a file.
02

Study summary

This study examines the efficacy of a psycho-educational intervention program, AgingPLUS, with regard to increasing middle-aged and older adults' engagement in physical activity.

Read the detailed description

AgingPLUS is a multi-component intervention program that addresses negative views of aging (NVOA), low internal control beliefs, and deficient goal planning as a risk cluster that keeps adults from engaging in health-promoting behavior. The program focuses on engagement in physical activity (PA) as the health behavior of choice. Engagement in PA is widely recognized as the best non-pharmacological, non-invasive, and cost-effective method of health promotion. Yet, only 20% of the adult population meets the recommended PA guidelines. This suggests that messages about the benefits of PA alone are not effective. Rather, it is essential to address the social-cognitive and motiva-tional mechanisms that prevent adults from adopting and maintaining a regular PA regimen. NVOA, low internal control beliefs, and deficient goal planning represent such a cluster of social-cognitive and motivational mechanisms.

Given this background, the specific aims and hypotheses of the proposed research are:

Aim 1: To conduct a randomized controlled trial examining the efficacy of the AgingPLUS program.

Aim 2: To test a conceptual model of the mechanisms underlying the intervention effects.

Aim 3: To conduct a 6-month follow-up to examine the longer-term effects of AgingPLUS.

Upon completion of this project, we expect to have successfully established evidence for the efficacy of the AgingPLUS program (Stage II of the NIH Stage Mode). The long-term goal is to develop AgingPLUS into a full-fledged evidence-based program that can be implemented in community settings (e.g., senior centers), and can serve as a fairly brief and cost-effective public health tool to promote healthy and successful aging.

03

Conditions studied

  • Physical Activity

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Keywords

  • Psychological Mechanisms
  • Social-Cognitive Mechanisms
04

Who can participate

Ages eligible
45 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adults who engage in less than 60 minutes of PA per week and who intend starting a physical exercise program.
  • English speaking.
  • Willingness to be randomized to one of two programs.
  • Willingness to take part in the physical fitness tests and wear an accelerometer.
  • Willingness to commit to follow-up testing (i.e., not moving out of the area during the study period).
  • Physician clearance to take part in a submaximal exercise test and to begin an exercise program.

Exclusion criteria

Exclusion Criteria:

  • Signs of cognitive decline (defined as more than 4 errors on the Short Portable Mental Status Questionnaire).
  • Severe vision and/or hearing loss (obtained by self-report).
  • Serious problems with mobility.
  • A history of neurological, mental, or substance abuse disorders.
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Care provider, Outcomes assessor)
Enrollment
402 participants (actual)

Study arms

  • Experimental
    Active Treatment Group

    This group will get the AgingPLUS intervention program which addresses negative views on aging, low internal control beliefs, and deficient goal planning skills.

    Behavioral: AgingPLUS

  • Placebo comparator
    Active Control Group

    This group will get a generic health education program, called the "10 Keys to Healthy Aging". The control program will control for the effect of social contact and will not address the intervention targets of the active treatment group. The health education program will only provide information related to some of the most important health conditions, such as cardiovascular disease, cancer, type 2 diabetes, and clinical depression, and how these conditions can be managed.

    Behavioral: Active Control Group

Interventions

  • BehavioralAgingPLUS

    The program consists of 2-hour meetings for a total of 4 weeks (total of 8 hours) and discusses (a) how negative views on aging and negative age stereotypes undermine adults' health-promoting behaviors; (b) how adults can take control of their own aging; and (c) how personal goals can be achieved through more effective goal planning and action plans.

  • BehavioralActive Control Group

    The program consists of 2-hour meetings for a total of 4 weeks (total of 8 hours) and discusses (a) four major health conditions that affect the lives of many middle-aged and older adults (e.g., cardiovascular disease, cancer, type 2 diabetes; clinical depression); and (b) how these conditions can be managed successfully.

06

What researchers measure

Primary outcomes

  1. Increased physical activity

    We expect that participants significantly increase their engagement in physical activity as assessed by an accelerometer.

    Time frame: This effect should be observable (1) at the Week-4 post-test, (2) the Week-8 post-test, and (3) the 6-Month post-test.

07

Study locations

1 site
  • Colorado State University
    Fort Collins, Colorado 80523-1570, United States
08

References and documents

Publications

  • Brothers A, Diehl M. Feasibility and Efficacy of the AgingPlus Program: Changing Views on Aging to Increase Physical Activity. J Aging Phys Act. 2017 Jul;25(3):402-411. doi: 10.1123/japa.2016-0039. Epub 2016 Dec 5. PubMed 27918687 ↗
  • Diehl M, Nehrkorn-Bailey A, Thompson K, Rodriguez D, Li K, Rebok GW, Roth DL, Chung SE, Bland C, Feltner S, Forsyth G, Hulett N, Klein B, Mars P, Martinez K, Mast S, Monasterio R, Moore K, Schoenberg H, Thomson E, Tseng HY. The AgingPLUS trial: Design of a randomized controlled trial to increase physical activity in middle-aged and older adults. Contemp Clin Trials. 2020 Sep;96:106105. doi: 10.1016/j.cct.2020.106105. Epub 2020 Aug 11. PubMed 32791322 ↗
  • Nehrkorn-Bailey AM, Rodriguez D, Forsyth G, Braun B, Burke K, Diehl M. Change in Views of Aging, Physical Activity, and Physical Health Over 8 Weeks: Results From a Randomized Study. J Aging Phys Act. 2023 Jan 28;31(4):666-678. doi: 10.1123/japa.2022-0133. Print 2023 Aug 1. PubMed 36708712 ↗

Study documents

PDFs hosted by the registry, ClinicalTrials.gov.

Individual participant data

Plan to share: No

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from May 2018 to primary completion in May 2023, 60 months.

Of 5,147 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's 60 months is above that.

Counting every sponsor, half of 5,207 studies reached it within 17 months; a quarter within 7 and three quarters within 36.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 23, 2017
First posted
Oct 3, 2017
StartActual
May 1, 2018
Primary completionActual
May 31, 2023
CompletionActual
May 31, 2023
Last update
Jun 19, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 19, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03299348
Responsible party
Manfred Diehl, PhD (Professor, Colorado State University) — Principal investigator
First posted
Oct 3, 2017
Start date
May 1, 2018
Primary completion
May 31, 2023
Completion
May 31, 2023
Last update
Jun 19, 2025

Study contacts

Manfred K. Diehl, PhD
principal investigator · Colorado State University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2025. You cannot join it, but the record below documents what was studied.

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