An observational study in Obesity, sponsored by The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School. Enrolling by invitation at 1 site in China. Open to participants aged 18 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-10-23.
Sponsored by The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Observational
This study focus on the cause of obesity and impacts of bariatric surgery on it.
Obesity patients and controls
Exclusion Criteria:
Patients with obesity already received bariatric surgery
Volunteers with normal body weight and already received abdominal surgery
Immunity cells
Ratio of immunity cells in circulating and adipose or liver tissue
Time frame: up to 5 years
Body weight and height
Body weight and height will be combined to report BMI in kg/m\^2
Time frame: up to 5 years
Insulin
Insulin (mIU/L) concentartions in serum and adipose tissue
Time frame: up to 5 years
Cytokine
Cytokines concentrations in circulating and adipose or liver tissue
Time frame: up to 5 years
Cognitive Assessment (MMSE)
Mini-Mental State Examination (MMSE) scores from 0-30, and the test means better cognition with a higher score.
Time frame: up to five years
Cognitive Assessment (MoCA)
The Montreal Cognitive Assessment (MoCA) scores from 0-30, and the test means better cognition with a higher score.
Time frame: up to 5 years
Cognitive Assessment (RBANS)
The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) scores from 0-800, and the test means better cognition with a higher score.
Time frame: up to 5 years
Cognitive Assessment (processing speed)
The Trial Making Test (TMT) provides a measure of processing speed, which consists of part A and part B (TMT-A and TMT-B). The time limits for performing the TMT-A and TMT-B are 180 and 300 seconds, respectively. Processing speed is estimated by the sum of the consuming time to complete TMT-A and TMT-B such that less time indicate faster processing speed.
Time frame: up to 5 years
Cognitive Assessment (executive function)
The Victoria Stroop Color-Word Test is a well-known measure of executive functioning. There are three indices including Stroop-dot, Stroop-word and Stroop-color word in the test. The color task consists of colored dots; the word task comprises ordinary words that are unrelated to the meaning of color; the color-word task consists of words written in color that indicate the meaning of the color, but the color of these words differs from the meaning of the word itself. The participants were asked to quickly read the color of the dots or Chinese words on the cards. The sum of consuming time taken to read the three cards is used as an index of executive function performance. Less time indicates better executive function.
Time frame: up to 5 years
brain structure and activation in fMRI
All patients underwent odor-induced task fMRI on a 3.0T MR scanner
Time frame: up to 5 years
Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.
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The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School