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Active, not recruitingNCT03288805Updated May 5, 2022

Cohort Study in South China

An observational study in Chronic Disease, sponsored by Min Xia. Active, not recruiting at 1 site in China. Open to participants aged 35 Years to 74 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-05-05.

Sponsored by Min Xia · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
110,000
Ages
35 Years to 74 Years
Sex
All
01

Study summary

Healthy Chinese residents from South China will be recruited and followed up for at least 4 years to evaluate the association between climate, diet and lifestyle and risks for the development of chronic diseases. Physical examination, questionnaire survey and biological sample collection will be conducted at baseline and the incidence of chronic diseases will be investigated during follow-up.

Read the detailed description

110,000 adult Chinese (35 to 74 years old) without chronic diseases and major disability who have been living in South China including Guangdong, Fujian, Guangxi and Hainan for more than 5 years will be recruited. All participants will be prospectively followed up for the incidence of chronic diseases (stroke, coronary heart disease, malignant neoplasms, chronic obstructive pulmonary diseases, diabetes and hypertension) and their risk factors (impaired glucose tolerance and obesity). Information about socio-demographic, diet, lifestyle, psychological status, medical history and current medication will be collected by questionnaires. Physical examinations including height, weight, waist and hip circumferences, blood pressure, fat mass and vital capacity will be conducted. Besides, blood, urine and fecal samples will be collected for further analysis. Annual meteorological data throughout the study period will also be collected. The associations between climate, diet and lifestyle and risks for chronic diseases will be evaluated.

02

Conditions studied

  • Chronic Disease

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03

Who can participate

Ages eligible
35 Years to 74 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Adult Chinese (35-74 years old) who have been living in South China including Guangdong, Fujian, Guangxi and Hainan provinces for more than 5 years.

Inclusion criteria

  • adult Chinese (35-74 years old) who have been living in South China including Guangdong, Fujian, Guangxi and Hainan provinces for more than 5 years.

Exclusion criteria

Exclusion Criteria:

  • any subject diagnosed with stroke, coronary heart disease, malignancy, chronic obstructive pulmonary disease, diabetes and hypertension.
  • any subject who suffer from major disability and cannot participate in the study.
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
110,000 participants (estimated)
Patient registry
No
Biospecimen retention
Samples with dna
05

What researchers measure

Primary outcomes

  1. Incidence of chronic disease

    Incidence of chronic disease, including stroke, coronary heart disease, cancer, chronic obstructive pulmonary disease, diabetes and hypertension

    Time frame: 4 years

Secondary outcomes

  1. Risk factors for chronic diseases

    Incidence of impaired glucose tolerance and obesity

    Time frame: 4 years

06

Study locations

1 site
  • Sun Yat-Sen University
    Guangzhou, Guangdong 510080, China
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03288805
Lead sponsor
Min Xia
Collaborators
Guangxi Medical University, Hainan Medical College, Guangzhou No.12 People's Hospital, Fujian Medical University, The First Affiliated Hospital of Xiamen University, Shenzhen Fifth People's Hospital, Guangzhou Medical University
Responsible party
Min Xia (Professor, Sun Yat-sen University) — Sponsor-investigator
First posted
Sep 20, 2017
Start date
Jan 1, 2017
Primary completion
Dec 31, 2030 (estimated)
Completion
Dec 31, 2030 (estimated)
Last update
May 5, 2022

Study contacts

Min Xia
principal investigator · School of Public Health,Nutrition and Food Hygiene,Sun Yat-sen University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in May 2022. You cannot join it, but the record below documents what was studied.

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