ClinicalTrials.gg
Active, not recruitingNCT03288805Updated May 5, 2022

Cohort Study in South China

An observational study in Chronic Disease, sponsored by Min Xia. Active, not recruiting at 1 site in China. Open to participants aged 35 Years to 74 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-05-05.

Sponsored by Min Xia · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
110,000
Ages
35 Years to 74 Years
Sex
All
01

Study summary

Healthy Chinese residents from South China will be recruited and followed up for at least 4 years to evaluate the association between climate, diet and lifestyle and risks for the development of chronic diseases. Physical examination, questionnaire survey and biological sample collection will be conducted at baseline and the incidence of chronic diseases will be investigated during follow-up.

Read the detailed description

110,000 adult Chinese (35 to 74 years old) without chronic diseases and major disability who have been living in South China including Guangdong, Fujian, Guangxi and Hainan for more than 5 years will be recruited. All participants will be prospectively followed up for the incidence of chronic diseases (stroke, coronary heart disease, malignant neoplasms, chronic obstructive pulmonary diseases, diabetes and hypertension) and their risk factors (impaired glucose tolerance and obesity). Information about socio-demographic, diet, lifestyle, psychological status, medical history and current medication will be collected by questionnaires. Physical examinations including height, weight, waist and hip circumferences, blood pressure, fat mass and vital capacity will be conducted. Besides, blood, urine and fecal samples will be collected for further analysis. Annual meteorological data throughout the study period will also be collected. The associations between climate, diet and lifestyle and risks for chronic diseases will be evaluated.

02

Conditions studied

  • Chronic Disease

Browse trials for

03

In context

Chronic Disease

781 studies on the registry are indexed under Chronic Disease; 144 are open to participants now.

This study's planned enrollment of 110,000 is above the median of 461 across 188 observational studies indexed under Chronic Disease.

Browse Chronic Disease studies →

Lead sponsor

Min Xia is the lead sponsor of 3 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
35 Years to 74 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Adult Chinese (35-74 years old) who have been living in South China including Guangdong, Fujian, Guangxi and Hainan provinces for more than 5 years.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • adult Chinese (35-74 years old) who have been living in South China including Guangdong, Fujian, Guangxi and Hainan provinces for more than 5 years.

Exclusion criteria

Exclusion Criteria:

  • any subject diagnosed with stroke, coronary heart disease, , , diabetes and hypertension.
  • any subject who suffer from major disability and cannot participate in the study.
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Cancer (malignancy)

Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.

Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.

COPD

Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.

05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
110,000 participants (estimated)
Patient registry
No
Biospecimen retention
Samples with dna
06

What researchers measure

Primary outcomes

  1. Incidence of chronic disease

    Incidence of chronic disease, including stroke, coronary heart disease, cancer, chronic obstructive pulmonary disease, diabetes and hypertension

    Time frame: 4 years

Secondary outcomes

  1. Risk factors for chronic diseases

    Incidence of impaired glucose tolerance and obesity

    Time frame: 4 years

07

Study locations

1 site
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Jan 2017 (actual). Primary completion is estimated for Dec 2030, 167 months after the start.

Of 86 non-industry observational studies under Chronic Disease, half reached primary completion within 35 months of starting (the median), counting those still running; a quarter within 14 and three quarters within 53. This study's planned 167 months is above that.

Counting every sponsor, half of 91 studies reached it within 37 months; a quarter within 14.

Chronic Disease covers many different conditions, not one, so the studies compared here vary widely. Read these figures as a rough guide.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 18, 2017
First posted
Sep 20, 2017
StartActual
Jan 1, 2017
Primary completionEst.
Dec 31, 2030
CompletionEst.
Dec 31, 2030
Last update
May 5, 2022
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 5, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03288805
Lead sponsor
Min Xia
Collaborators
Guangxi Medical University, Hainan Medical College, Guangzhou No.12 People's Hospital, Fujian Medical University, The First Affiliated Hospital of Xiamen University, Shenzhen Fifth People's Hospital, Guangzhou Medical University
Responsible party
Min Xia (Professor, Sun Yat-sen University) — Sponsor-investigator
First posted
Sep 20, 2017
Start date
Jan 1, 2017
Primary completion
Dec 31, 2030 (estimated)
Completion
Dec 31, 2030 (estimated)
Last update
May 5, 2022

Study contacts

Min Xia
principal investigator · School of Public Health,Nutrition and Food Hygiene,Sun Yat-sen University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in May 2022. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion