An interventional study of I-PRF in Periodontoclasia, Gingiva; Injury and Condition, sponsored by Bezmialem Vakif University. Completed at 1 site in Turkey. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-09-09.
Sponsored by Bezmialem Vakif University · Not applicable, Interventional, and Treatment
The main objective of this study is to investigate whether the for individuals with thin gingival thickness who are susceptible to gingival recession, the investigators will use i-PRF with microneedle to increase gingival thickness without the need for surgical procedures
Due to the thin gingival phenotype, gingival recession is a problem. The investigators aimed to increase the gingival thickness using i-PRF with microneedle without considering surgical procedures, considering the positive effects of platelet concentrations on revascularization and wound healing in individuals with bone defect, fenestration and gingival thickness which are prone to gingival recession .
2,217 studies on the registry are indexed under Wounds and Injuries; 441 are open to participants now.
This study's enrollment of 29 is below the median of 70 across 1,424 interventional studies indexed under Wounds and Injuries.
Browse Wounds and Injuries studies →Bezmialem Vakif University is the lead sponsor of 354 studies on the registry; 59 are open to participants now.
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Exclusion Criteria:
Venous blood will be taken from the patient every session and I-PRF will be created in the centrifuge.I-PRF injected on one side of bilateral thin gingival thickness.Apply once a week and one month after the end of the injections, the patient will be called to the control.
Other: I-PRF
Venous blood will be taken from the patient every session and I-PRF will be created in the centrifuge.Microneedle application plus I-PRF injected on the other side in patients with bilateral region with thin gingival phenotype.Apply once a week and one month after the end of the injections, the patient will be called to the control.
Other: I-PRF
Venous blood will be taken from the patient every session and I-PRF will be created in the centrifuge.I-PRF injected on one side of bilateral thin gingival thickness.Microneedle application plus I-PRF injected on the other side in patients with bilateral region with thin gingival phenotype.Apply once a week and one month after the end of the injections, the patient will be called to the control.
Also known as: I-PRF and Microneedling
Gingival thickness (mm)
Change in clinical measures of gingival thickness
Time frame: 2 months
Plaque Index (PI)
Change in clinical measures of gingival parameters
Time frame: 2 months
Gingival Index (GI)
Change in clinical measures of gingival parameters
Time frame: 2 months
Bleeding on probing (BOP)
Change in clinical measures of gingival parameters
Time frame: 2 months
Clinical attachment level (CAL)
Change in clinical measures of gingival parameters
Time frame: 2 months
Probing pocket depth (PD)
Change in clinical measures of gingival parameters
Time frame: 2 months
Plan to share: Undecided
Ran from Apr 2017 to primary completion in Jan 2018, 8 months.
Of 546 non-industry interventional studies with no phase under Wounds and Injuries, half reached primary completion within 24 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 49. This study's 8 months is below that.
Counting every sponsor, half of 599 studies reached it within 24 months; a quarter within 9 and three quarters within 48.
Wounds and Injuries covers many different conditions, not one, so the studies compared here vary widely. Read these figures as a rough guide.
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This study is completed, as verified in Sep 2020. You cannot join it, but the record below documents what was studied.
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