An observational study in Heparin-Induced Thrombocytopenia, Thrombosis and Biomarkers, sponsored by Wuhan Asia Heart Hospital. Status unknown. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-08-31.
Sponsored by Wuhan Asia Heart Hospital · Observational
Heparin induced thrombocytopenia (HIT) is a kind of catastrophic thrombotic complications after the application of heparin. If HIT without treatment, death rate is as high as 30% to 50%. Early diagnosis of HIT and prevention of thrombosis is very important.
This study is planned to assess the use of thrombotic biomarkers in patients with HIT, including thrombin-antithrombin complex, d-dimer, fibrin degradation products and Thrombelastograghy monitoring . These biomarkers are monitored in 5-14 days post-operation to assess the risk of thrombosis in HIT patients. All patients were followed up for 30 days, and clinical outcomes, including new thrombus and death, were recorded during follow-up.
Patients are those who receiving cardiac surgery, including valve replacementheart,Coronary Artery Bypass Grafting,aorta replacement etc.
Exclusion Criteria:
The patients with heparin-induced thrombocytopenia.
Diagnostic Test: HIT with thrombosis
The patients with heparin-induced thrombocytopenia with thrombosis.
Diagnostic Test: HIT with thrombosis
The patients without heparin-induced thrombocytopenia and heparin-induced thrombocytopenia with thrombosis.
Testing thrombin-antithrombin complex, d-dimer, fibrin degradation products and Thrombelastograghy.
Thrombotic event
New thrombosis, including deep venous thrombosis,pulmonary embolism,Cerebral infarction,superior mesenteric artery embolism,artery embolism etc.
Time frame: 30 days
Deaths
All-cause deaths
Time frame: 30 days
No study locations are listed for this record.
Plan to share: Undecided — We are going to make individual participant data (IPD) available to other researchers after our paper published.
No publications or documents are linked to this record.
This study is status unknown, as verified in Aug 2017. You cannot join it, but the record below documents what was studied.
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Wuhan Asia Heart Hospital