CClinicalTrials.gg
Status unknownNCT03263156Updated Apr 27, 2021

A Brief Parent-based Sleep Intervention for ADHD Children

An interventional study of Sleep hygiene practices and behavioural intervention in ADHD and Insomnia, sponsored by The University of Hong Kong. Status unknown at 2 sites in Hong Kong. Open to participants aged 6 Years to 12 Years. Per ClinicalTrials.gov, last updated 2021-04-27.

Sponsored by The University of Hong Kong · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Apr 2021), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
6 Years to 12 Years
Sex
All
01

Study summary

Sleep problems are very common in children with ADHD, with a prevalence rate as high as 73%, and often pose significant challenges and stress to the families. Sleep problems in ADHD children are strongly associated with the exacerbation of daytime symptoms, impaired physical health, and poor parental mental health. The present study is a randomised controlled trial to compare the effects of a parent-based sleep intervention for children with ADHD (aged 6-12). Eligible participants will be randomised to either intervention (two face-to-face consultation sessions and one follow-up phone call) or waiting-list control condition. Assessments will be conducted at pre-treatment (baseline), one-week after the intervention (post-treatment), and 3 months after the intervention.

02

Conditions studied

  • ADHD
  • Insomnia

Keywords

  • sleep
  • ADHD
  • behavioural intervention
  • insomnia
03

Who can participate

Ages eligible
6 Years to 12 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Aged 6-12 years old;
  • With a clinical diagnosis of ADHD (any subtype), as confirmed by the Diagnostic Interview Schedule for Children-version-IV (DISC-IV);
  • With parent-reported insomnia (difficulty initiating sleep and/or maintaining sleep).

Exclusion criteria

Exclusion Criteria:

  • Children with a serious medical condition (e.g. severe cerebral palsy) or intellectual disability (IQ\<70);
  • Children with a neurological and/or medical condition that may lead to disordered sleep;
  • Suspected clinical sleep disorders (e.g. obstructive sleep apnea, OSA) that may potentially contribute to a disruption in sleep continuity and quality, as assessed by the Children's Sleep Habits Questionnaire (CSHQ). If the child is suspected of a clinical sleep disorder, he/she will be referred to appropriate services;
  • Children who are already receiving specialised help (behavioural intervention) for their sleep from a psychologist or at a specialized sleep clinic.
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
60 participants (estimated)

Study arms

  • Experimental
    Intervention group

    The intervention will involve two face-to-face consultation sessions and one follow-up phone call with parents to help them learn sleep hygiene practices and specific behavioural strategies to improve their child's sleep and follow up on the progress.

    Behavioral: Sleep hygiene practices and behavioural intervention

  • No intervention
    Waiting-list control

    Children in the waiting-list control group will receive usual clinical care.

Interventions

  • BehavioralSleep hygiene practices and behavioural intervention

    The first session will involve the provision of sleep-related psycho-education (e.g. sleep hygiene practices) and specific strategies to tackle problematic sleep-related behaviours, as well as collaborative goal setting and development of management plan tailored to the child's sleep problem for the next two weeks. The second session will involve a review of the sleep diary and a reinforcement of learned strategies, and focus on problem-solving to tackle any issues that have emerged from implementing the behavioural strategies at home. A follow-up phone call will be made two weeks later to provide parents with an opportunity to ask any further questions and to consolidate learned strategies and further troubleshoot.

05

What researchers measure

Primary outcomes

  1. Child: Change of child's sleep

    Change of the child's sleep measured by the Children's Sleep Habits Questionnaire (CSHQ), and sleep problems rated by parent (none, mild, moderate, severe)

    Time frame: Baseline, 1-week and 3-month posttreatment

Secondary outcomes

  1. Child: Change of daytime sleepiness

    Pediatric Daytime Sleepiness Scale (PDSS) - parent report

    Time frame: Baseline, 1-week and 3-month posttreatment

  2. Child: Change of other sleep measures

    Daily sleep diary and actigraphic assessment for consecutive seven days

    Time frame: Baseline, 1-week and 3-month posttreatment

  3. Child: Change of ADHD symptoms

    Strengths and Weaknesses of ADHD Symptoms (SWAN) - parent report

    Time frame: Baseline, 1-week and 3-month posttreatment

  4. Child: Change of child's behaviour & other clinical symptoms

    Strengths and Difficulties Questionnaire - parent report; Child Behavior Checklist (CBCL) - parent report

    Time frame: Baseline, 1-week and 3-month posttreatment

  5. Child: Change of quality of life

    Pediatric Quality of Life Inventory 4.0 - parent proxy report (PedsQL) - parent report

    Time frame: Baseline, 1-week and 3-month posttreatment

  6. Child: Change of cognitive performance (sustained attention)

    Continuous Performance Test (CPT)

    Time frame: Baseline, 1-week and 3-month posttreatment

  7. Child: Change of cognitive performance (auditory attention span)

    Digit Span

    Time frame: Baseline, 1-week and 3-month posttreatment

  8. Child: Change of cognitive performance (working memory)

    N-back

    Time frame: Baseline, 1-week and 3-month posttreatment

  9. Child: Change of cognitive performance (cognitive processing)

    Letter-digit substitution task

    Time frame: Baseline, 1-week and 3-month posttreatment

  10. Child: Change of cognitive performance (cognitive flexibility)

    Bergs Card Sorting Test (BCST)

    Time frame: Baseline, 1-week and 3-month posttreatment

  11. Child: Change of cognitive performance (planning skills)

    Tower of London (TOL)

    Time frame: Baseline, 1-week and 3-month posttreatment

  12. Change of parental self-reported sleep quality

    Pittsburgh Sleep Quality Index (PSQI)

    Time frame: Baseline, 1-week and 3-month posttreatment

  13. Change of parental insomnia symptoms

    Insomnia Severity Index (ISI)

    Time frame: Baseline, 1-week and 3-month posttreatment

  14. Change of parental daytime sleepiness

    Epworth Sleepiness Questionnaire (ESS)

    Time frame: Baseline, 1-week and 3-month posttreatment

  15. Change of parental sleep parameters as measured by actigraphy

    Actigraphic sleep parameters

    Time frame: Baseline, 1-week and 3-month posttreatment

  16. Change of parental sleep hygiene practice

    Sleep Hygiene Index (SHI)

    Time frame: Baseline, 1-week and 3-month posttreatment

  17. Change of parental stress

    Parental Stress Index - Short Form (PSI-SF)

    Time frame: Baseline, 1-week and 3-month posttreatment

  18. Change of parental mood symptoms

    Depression Anxiety Stress Scales - 21 item (DASS-21)

    Time frame: Baseline, 1-week and 3-month posttreatment

  19. Change of parental daytime fatigue

    Multidimensional Fatigue Inventory (MFI)

    Time frame: Baseline, 1-week and 3-month posttreatment

  20. Parent's satisfaction to the treatment

    Treatment satisfaction rating scale

    Time frame: Baseline, 1-week and 3-month posttreatment

06

Study locations

2 of 2 sites recruiting
  • Child and Adolescent Psychiatric Service Clinic, New Territories East Cluster (NTEC), Hospital Authority
    Hong Kong, Hong Kong
    Recruiting
  • Sleep Research Clinic & Laboratory, Department of Psychology, The University of Hong Kong
    Hong Kong, Hong Kong
    Recruiting
07

References and documents

Study documents

  • Study protocol · Sep 29, 2016

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

08

Registry details

Key details

Study ID
NCT03263156
Lead sponsor
The University of Hong Kong
Collaborators
Chinese University of Hong Kong
Responsible party
Dr. Shirley Xin Li (Assistant Professor, The University of Hong Kong) — Principal investigator
First posted
Aug 28, 2017
Start date
Apr 1, 2017
Primary completion
Dec 31, 2021 (estimated)
Completion
Dec 31, 2021 (estimated)
Last update
Apr 27, 2021

Study contacts

Shirley Xin Li, PhD,DClinPsy
Contact
shirley.li@hku.hk
852-39177035
Shirley Xin Li, PhD,DClinPsy
principal investigator · Department of Psychology, The University of Hong Kong

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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