An interventional study of Angelica gigas N. extract and Placebo in Hyperglycemia, sponsored by Chonbuk National University Hospital. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-08-22.
Sponsored by Chonbuk National University Hospital · Not applicable, Interventional, and Prevention
This study was conducted to investigate the effects of daily supplementation of Angelica gigas N. extract on improvement of Hyperglycemia .
This study was a 8 weeks, randomized, double-blind, placebo-controlled 2×2 cross-over design human trial. Twenty subjects were randomly divided into Angelica gigas N. extract or a placebo group. Fasting and postprandial glucose profiles during oral glucose tolerance test (OGTT) were assessed before and after the intervention.
Exclusion Criteria:
Laboratory test by show the following results
capsules(2cap/d, 1,000mg/d) for 8 weeks.
Dietary Supplement: Angelica gigas N. extract
Placebo for 8 weeks
Dietary Supplement: Placebo
capsules(2cap/d, 1,000mg/d) for 8 weeks.
Placebo for 8 weeks
Changes of blood glucose during OGTT (oral glucose tolerance test)
Changes of fasting and postprandial glucose during OGTT were assessed before and after the intervention.
Time frame: 8 weeks
Changes of blood insulin during OGTT
Changes of blood insulin during OGTT were assessed before and after the intervention.
Time frame: 8 weeks
Changes of Homeostatic model assessment-insulin resistance
Changes of physiological parameter{Homeostatic model assessment-insulin resistance(mg/dl)} were assessed before and after the intervention
Time frame: 8 weeks
Changes of Homeostatic model assessment-beta-cell
Changes of physiological parameter{Homeostatic model assessment-beta-cell(mg/dl)} were assessed before and after the intervention
Time frame: 8 weeks
Changes of HbA1c
Changes of HbA1c(%) were assessed before and after the intervention
Time frame: 8 weeks
Changes of Adiponectin, Leptin
Changes of Adiponectin and Leptin(ng/ml) were assessed before and after the intervention
Time frame: 8 weeks
Changes of lipid profile
Changes of lipid profile were assessed before and after the intervention
Time frame: 8 weeks
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.
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Chonbuk National University Hospital