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CompletedNCT03241979Updated Apr 21, 2021

THRIVE in Pediatric Laryngeal Microsurgery

An observational study in Laryngoscopy, sponsored by Seoul National University Hospital. Completed at 1 site in Korea, Republic of. Open to participants aged Up to 6 Years. Per ClinicalTrials.gov, last updated 2021-04-21.

Sponsored by Seoul National University Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
30
Ages
Up to 6 Years
Sex
All
01

Study summary

Transnasal High-flow rapid-insufflation ventilatory exchange (THRIVE) has been shown to benefit oxygenation, ventilation and upper airway patency in a range of clinical scenarios, however its use in spontaneously breathing pediatric patients undergoing tubeless airway surgery has not been described. This is a physiologic study that evaluates the feasibility of THRIVE during pediatric airway surgery under self-respiration.

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Conditions studied

  • Laryngoscopy
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In context

Lead sponsor

Seoul National University Hospital is the lead sponsor of 1,860 studies on the registry; 275 are open to participants now.

Of its 12 completed or terminated interventional studies of FDA-regulated products, 2 (17%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Up to 6 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

pediatric patients

Inclusion criteria

  • pediatric patients undergoing laryngeal microsurgery with spontaneous ventilation

Exclusion criteria

Exclusion Criteria:

  • Severe gastrointestinal reflux disease Neuromuscular disease Central hypoventilation
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
30 participants (actual)
Patient registry
No

Groups and cohorts

  • laryngeal microsurgery
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What researchers measure

Primary outcomes

  1. number of low saturation events

    oxygen saturation decrease lower than 90%

    Time frame: Intraoperative

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Study locations

1 site
  • SNUH
    Seoul, Jongro Gu 15710, Korea, Republic of
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References and documents

Publications

  • Kim EH, Ji SH, Lee JH, Kim JT, Jang YE, Kwon SK, Kim HS. Use of high-flow nasal oxygen in spontaneously breathing pediatric patients undergoing tubeless airway surgery: A prospective observational study. Medicine (Baltimore). 2022 Jul 8;101(27):e29520. doi: 10.1097/MD.0000000000029520. PubMed 35801795 ↗

Individual participant data

Plan to share: Undecided

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 21, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03241979
Lead sponsor
Seoul National University Hospital
Responsible party
Hee-Soo Kim (professor, Seoul National University Hospital) — Principal investigator
First posted
Aug 8, 2017
Start date
Aug 7, 2017
Primary completion
Jun 3, 2019
Completion
Jun 3, 2019
Last update
Apr 21, 2021

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2021. You cannot join it, but the record below documents what was studied.

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