An observational study in Diastolic Dysfunction and Endothelial Dysfunction, sponsored by Clinica ARS Medica. Status unknown at 1 site in Switzerland. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-08-23.
Sponsored by Clinica ARS Medica · Observational
This is a monocentric pilot study to assess the safety profile of a 30-meter deep underwater diving using 3 different type of gas mixtures: AIR (21% O2 and 79% N2), NITROX 32 (32% O2 And 68% N2) and TRIMIX (21% O2, 44% N2 and 35% He).
The participants will be measured for vital parameters, blood samples and transthoracic cardiac ultrasound before diving (baseline).
Participants will be requested to perform recreational dive, which does not require particular decompression stops, at a depth of 30 meters with a 30 minutes botton time. 20 minutes after dive the same measurements as baseline will be repeated, once at rest and once after a physical effort by performing a series of 10 bending on the legs (squats). The day after dive, the participants will be interviewed by phone (FOLLOW-UP) by a physician. It will be required to report any unusual event, MDD symptom, or neurological complication.
Same procedure will be repeated with three different type of blends (AIR, NITROX, TRIMIX).
Clinica ARS Medica is the lead sponsor of 2 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Healty volunteer divers
Exclusion Criteria:
Three dives with different gas mixture : AIR (21% di O2 e 79% di N2), NITROX 32 (32% di O2 e 68% di N2) and TRIMIX (21% O2, 44% N2 e 35% He)
Diagnostic Test: Transthoracic echocardiography · Diagnostic Test: Blood samples
Diagnostic test done prior and after the dive
Diagnostic test done prior and after the dive
Best gas mixture
Best gas mixture with minimal cardiac function impact (endothelial stress)
Time frame: 1 month
diastolic function evaluation
diastolic function evaluated after a dive with three different gas mixtures
Time frame: 1 month
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Aug 2017. You cannot join it, but the record below documents what was studied.
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Clinica ARS Medica