A Phase 3 interventional study of Platelet Rich Plasma and Cellerate in Arthroplasty, Replacement, sponsored by Salt Lake Orthopedic Clinic. Completed. Open to participants aged 50 Years to 85 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-05-18.
Sponsored by Salt Lake Orthopedic Clinic · Phase 3, Interventional, and Treatment
3 cohorts of total joint patient of 30 members each were randomized to receive PRP or Activated Collegen or no additive were studied for status of the wound at 6 weeks and recorded all complications, infections and reoperations. The three groups were than compared for statistical analysis
Background: Wound healing remains a concern in primary total joint arthroplasty given the risk of deep infections arising from hematomas, wound separations, and superficial infections. If wound additives can prevent these early complications, their universal application would be cost effective. This study examined whether two wound additives, Platelet-Rich Plasma (PRP) and CellerateRX® (activated collagen), would improve postoperative wound healing and reduce complications in primary total joint arthroplasty.
Methods: A prospective, randomized, controlled study using three cohorts with 30 patients each (Group 1: PRP, Group 2: activated collagen, Group 3: control) were examined postoperatively at two and six weeks, at which time the following data were recorded: six wound measurements, total postoperative blood loss, complications of superficial infections, and reoperations.
This is the only study on the registry with Salt Lake Orthopedic Clinic as lead sponsor.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
30cc of PRP was administered at closure of wound
Biological: Platelet Rich Plasma
1gm of Cellerate was administered at closure of wound
Biological: Cellerate
Also known as: PRP
Also known as: Activated college
Wound Status
wound hematoma, dehiscence, superficial infection
Time frame: 6 weeks post operative
No study locations are listed for this record.
Plan to share: No — no plan on sharing data
No publications or documents are linked to this record.
This study is completed, as verified in May 2017. You cannot join it, but the record below documents what was studied.
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