ClinicalTrials.gg
CompletedNCT03155633CRSUpdated May 16, 2017

Run, Recovery, Repeat, Always Healthy ("Corre, Recupera, Repite, Siempre Saludable")

An interventional study of Athletics track and Elliptical machine in Physical Exertion, sponsored by Universitat Jaume I. Completed. Open to participants aged 30 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-05-16.

Sponsored by Universitat Jaume I · Not applicable, Interventional, and Other

From the registry’s dates

  • Registered 10 months after the study started (first participant enrolled Jun 2016, registered Apr 2017).
Phase
Not applicable
Study type
Interventional
Enrollment
98
Allocation
Randomized
Ages
30 Years to 45 Years
Sex
All
01

Study summary

This study has as main objective to know how the processes of recovery are realized after a race of marathon. For this, the participants of a marathon race are divided into three work groups during the 9 days post-marathon, one with rest in the recovery period, another with continuous race three sessions every 48h and another with three sessions of elliptical every 48h .

Read the detailed description

The marathon runners suffer a high fatigue, as has been studied by different investigations, the proposal of this study is to know how the recovery processes are produced in runners who have completed a 42km test.

To do this, baseline measurements of the runners have been made through stress tests and determinations of biomarkers in blood and urine. Subsequently blood and urine samples were taken the day before the marathon test and blood and urine samples were then taken again on arrival at 24h, 48h, 96h, 144h, and 196h.

At the same time, an intervention was carried out in the recovery phase, with the runners in three groups. The first one performed rests during the 9 days after the race, the second performed continuous race monitored every 48h from the end of the race, and the third group performed aerobic work on an elliptical machine under the same conditions as the group of Continuous race

02

Conditions studied

  • Physical Exertion

Keywords

  • Marathon, runners, biomarkers, recovery
03

In context

Lead sponsor

Universitat Jaume I is the lead sponsor of 80 studies on the registry; 19 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
30 Years to 45 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Adults healthy with 30-45 years
  • BMI between 16-24,99
  • Time in marathon between 3h-4h in men
  • Time in marathon between 3h:30min-4h:40min in women

Exclusion criteria

Exclusion Criteria:

  • Having heart disease
  • Having kidney disease
  • Taking a medication on an ongoing basis
05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
98 participants (actual)

Study arms

  • No intervention
    Rest Group

    Rest during the 9 days after the race

  • Experimental
    Running Group

    Running at 95-105% aerobic Threshold on athletics track 48h, 96h, 144h after the race. Control heart devices

    Other: Athletics track

  • Experimental
    Elliptical Group

    Running at 95-105% aerobic Threshold on elliptical machine 48h, 96h, 144h after the race. Control heart devices

    Other: Elliptical machine

Interventions

  • OtherAthletics track

    Running at 95-105% aerobic Threshold on athletics track 48h, 96h, 144h after the race. Control heart devices

  • OtherElliptical machine

    Running at 95-105% aerobic Threshold on elliptical machine 48h, 96h, 144h after the race. Control heart devices

06

What researchers measure

Primary outcomes

  1. Change in the Blood Physiological parameters

    Blood test

    Time frame: baseline, 0, 24, 48, 96, 144 and 192 hours post-race

  2. Analysis of tne changes in the Physical activity data

    Physical activity measured by wearing accelerometer devices. Physical activity defined as sedentary, light, moderate and vigorous. The aim to wear accelerometers devices is to monitor individuals during recovery time post-marathon race

    Time frame: One month before the pre-race, accelerometers were worn during seven days. Accelerometers were also worn during nine days starting from the night before the marathon race

  3. Change in the Urin Physiological parameters

    Urin test

    Time frame: baseline, 0, 48, 96, 144 and 192 hours post-race

Secondary outcomes

  1. Self-reported questionnaire

    Personal questionnaire asking for social and training habits

    Time frame: One month before the race day

  2. Strength level

    Squat Jump (cm). Two jumps per person

    Time frame: pre-marathon race and 0, 48, 96, 144 hours post-marathon race

  3. Analysis of the change of body mass index

    BMI

    Time frame: one month before the marathon race day, 24 hours before the marathon race, 2 hours before the marathon race and 10 minutes after the marathon race

  4. Physical Condition

    Maximal oxygen consumption

    Time frame: One month before the marathon race day

  5. Body composition

    Bioimpedance analysis

    Time frame: One month before the marathon race day

  6. Heart rate

    Recording the number of contractions of the heart per minute (bpm) by using a heart rate monitor during all the marathon race

    Time frame: Through marathon completion, an average of 4 hours

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • Knechtle B, Nikolaidis PT, Zingg MA, Rosemann T, Rust CA. Differences in age of peak marathon performance between mountain and city marathon running - The 'Jungfrau Marathon' in Switzerland. Chin J Physiol. 2017 Feb 28;60(1):11-22. doi: 10.4077/CJP.2017.BAE400. PubMed 28052642 ↗
  • Roca E, Nescolarde L, Lupon J, Barallat J, Januzzi JL, Liu P, Cruz Pastor M, Bayes-Genis A. The Dynamics of Cardiovascular Biomarkers in non-Elite Marathon Runners. J Cardiovasc Transl Res. 2017 Apr;10(2):206-208. doi: 10.1007/s12265-017-9744-2. Epub 2017 Apr 5. PubMed 28382580 ↗
  • Santos VC, Sierra AP, Oliveira R, Cacula KG, Momesso CM, Sato FT, Silva MB, Oliveira HH, Passos ME, de Souza DR, Gondim OS, Benetti M, Levada-Pires AC, Ghorayeb N, Kiss MA, Gorjao R, Pithon-Curi TC, Cury-Boaventura MF. Marathon Race Affects Neutrophil Surface Molecules: Role of Inflammatory Mediators. PLoS One. 2016 Dec 2;11(12):e0166687. doi: 10.1371/journal.pone.0166687. eCollection 2016. PubMed 27911915 ↗
  • Niemela M, Kangastupa P, Niemela O, Bloigu R, Juvonen T. Individual responses in biomarkers of health after marathon and half-marathon running: is age a factor in troponin changes? Scand J Clin Lab Invest. 2016 Nov;76(7):575-580. doi: 10.1080/00365513.2016.1225122. Epub 2016 Sep 9. PubMed 27609306 ↗
  • Kim YJ, Ahn JK, Shin KA, Kim CH, Lee YH, Park KM. Correlation of Cardiac Markers and Biomarkers With Blood Pressure of Middle-Aged Marathon Runners. J Clin Hypertens (Greenwich). 2015 Nov;17(11):868-73. doi: 10.1111/jch.12591. Epub 2015 Jun 13. PubMed 26073606 ↗
  • Tojima M, Noma K, Torii S. Changes in serum creatine kinase, leg muscle tightness, and delayed onset muscle soreness after a full marathon race. J Sports Med Phys Fitness. 2016 Jun;56(6):782-8. Epub 2015 Feb 10. PubMed 25665742 ↗
  • Knechtle B, Knechtle P, Rosemann T, Lepers R. Personal best marathon time and longest training run, not anthropometry, predict performance in recreational 24-hour ultrarunners. J Strength Cond Res. 2011 Aug;25(8):2212-8. doi: 10.1519/JSC.0b013e3181f6b0c7. PubMed 21642857 ↗
  • Knechtle B, Knechtle P, Barandun U, Rosemann T, Lepers R. Predictor variables for half marathon race time in recreational female runners. Clinics (Sao Paulo). 2011;66(2):287-91. doi: 10.1590/s1807-59322011000200018. PubMed 21484048 ↗
  • Martinez-Navarro I, Montoya-Vieco A, Collado E, Hernando B, Panizo N, Hernando C. Muscle Cramping in the Marathon: Dehydration and Electrolyte Depletion vs. Muscle Damage. J Strength Cond Res. 2022 Jun 1;36(6):1629-1635. doi: 10.1519/JSC.0000000000003713. Epub 2020 Aug 12. PubMed 32796418 ↗

Individual participant data

Plan to share: Yes — The data are administered by the Investigator Principal, other researchers must request the data they need by written request

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from Jun 2016 to primary completion in Oct 2016, 4 months.

How these figures are worked out, and which studies are left out of them.

Registered
Apr 26, 2017
First posted
May 16, 2017
StartActual
Jun 1, 2016
Primary completionActual
Oct 20, 2016
CompletionActual
Nov 30, 2016
Last update
May 16, 2017
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on May 16, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03155633
Lead sponsor
Universitat Jaume I
Collaborators
Fundación Trinidad Alfonso, Fundación Hospitales NISA, SD. Correcaminos
Responsible party
Carlos Hernando (Ph D. Director of Sports Service, Universitat Jaume I) — Principal investigator
First posted
May 16, 2017
Start date
Jun 1, 2016
Primary completion
Oct 20, 2016
Completion
Nov 30, 2016
Last update
May 16, 2017

Study contacts

Carlos Hernando
principal investigator · Universitat Jaume I

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2017. You cannot join it, but the record below documents what was studied.

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