CClinicalTrials.gg
CompletedNCT03071237IPA-OriginUpdated Feb 19, 2019

The Origin of Infrapyloric Artery

An observational study in Stomach Neoplasm, sponsored by Peking University. Completed at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-02-19.

Sponsored by Peking University · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
429
Ages
18 Years and older
Sex
All
01

Study summary

Infrapyloric artery(IPA) is of great importance for gastric cancer patients. According to previous study, the origin of IPA varies greatly among different studies. This trial aims to tell the distribution of IPA origin in Chinese patients.

Read the detailed description

Infrapyloric artery(IPA) is of great importance for gastric cancer patients. In early gastric cancer patients, the pylorus-preserving gastrectomy requires the preserving of IPA. In advanced gastric cancer patients, the subgroup of No. 6 lymph node might be associated with IPA. In Japanese Gastric Cancer Association(JGCA) gastric cancer classification guidelines, the No. 6 lymph nodes is defined as lymph nodes along the first branch and proximal part of the right gastroepiploic artery(RGEA) down to the confluence of the right gastroepiploic vein and the anterior superior pancreatoduodenal vein. However,if IPA origins from the gastroduodenal artery(GDA) or anterior superior pancreatoduodenal artery(ASPDA), the lymph nodes along the IPA can not be grouped into the No. 6 lymph nodes. Thus, a new definition of No. 6 lymph nodes is needed on the basis of the origin of IPA.

Previous studies about IPA origin are few and the origin of IPA varies greatly among different studies.

02

Conditions studied

  • Stomach Neoplasm

Browse trials for

Keywords

  • infrapyloric artery
  • gastric cancer
03

In context

Stomach Neoplasms

2,851 studies on the registry are indexed under Stomach Neoplasms; 864 are open to participants now.

This study's enrollment of 429 is above the median of 274 across 670 observational studies indexed under Stomach Neoplasms.

Browse Stomach Neoplasms studies →

Lead sponsor

Peking University is the lead sponsor of 411 studies on the registry; 122 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Probability sample

Study population

Patients with gastric cancer who needs to receive total or distal gastrectomy.

Inclusion criteria

  • Patients with gastric cancer who needs to receive total or distal gastrectomy.
  • Signed informed consent

Exclusion criteria

Exclusion Criteria:

  • IPA not dissected, photo-taken or video-recorded.
05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
429 participants (actual)
Patient registry
No

Groups and cohorts

  • Observational group

    Patients who would receive total gastrectomy or distal gastrectomy are enrolled in to the study and this group. An optional reconstruction of IPA by enhanced CT scan can be performed before surgery but not a definite require. During the operation, IPA origin location will be photo-taken or video-recorded before its transection.

    Procedure: Gastrectomy

Interventions

  • ProcedureGastrectomy

    Patients with gastric cancer that needs receiving total or distal gastrectomy. During the surgery, IPA needs to be exposed and transected.

    Also known as: surgery

06

What researchers measure

Primary outcomes

  1. Distribution of IPA origin

    The percentage of IPA origin from GDA, ASPDA and RGEA.

    Time frame: Immediately after surgery

Secondary outcomes

  1. Reconstruction rate of IPA by CT scan

    The rate of identification of IPA origin by reconstruction of CT scan.

    Time frame: Immediately after the reconstruction of CT scan.

07

Study locations

1 site
  • Beijing Cancer Hospital
    Beijing, Beijing 100142, China
08

References and documents

Publications

  • Haruta S, Shinohara H, Ueno M, Udagawa H, Sakai Y, Uyama I. Anatomical considerations of the infrapyloric artery and its associated lymph nodes during laparoscopic gastric cancer surgery. Gastric Cancer. 2015 Oct;18(4):876-80. doi: 10.1007/s10120-014-0424-5. Epub 2014 Sep 17. PubMed 25228163 ↗
  • Shinohara H, Kurahashi Y, Kanaya S, Haruta S, Ueno M, Udagawa H, Sakai Y. Topographic anatomy and laparoscopic technique for dissection of no. 6 infrapyloric lymph nodes in gastric cancer surgery. Gastric Cancer. 2013 Oct;16(4):615-20. doi: 10.1007/s10120-012-0229-3. Epub 2013 Jan 13. PubMed 23314832 ↗
  • Miao R, Qu J, Li Z, Wang D, Yu J, Zang W, Li Y, Liu F, Zhang J, Song W, Ye K, Yan S, Wang W, Ren S, Zang L, Jing C, Zhang L, Wang K, Fu W, Fan L, Liang B, Zhao G, Cai J, Yang L, Zhu J, You J, Yang K, Huang Q, Niu Z, Ning N, Qiu X, Ji G, Liang F, Huang H, Gao C, Shan F, Li S, Jia Y, Zhang L, Ying X, Zhang Y, Bu Z, Su X, Zhao G, Li Z, Ji J. Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin). Chin J Cancer Res. 2018 Oct;30(5):500-507. doi: 10.21147/j.issn.1000-9604.2018.05.03. PubMed 30510361 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 19, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03071237
Lead sponsor
Peking University
Responsible party
Jiafu Ji (MD, Peking University) — Principal investigator
First posted
Mar 6, 2017
Start date
Mar 4, 2017
Primary completion
Dec 31, 2017
Completion
Dec 31, 2017
Last update
Feb 19, 2019

Study contacts

Ziyu Li, M.D.
principal investigator · Gastrointestinal Cancer Center, Peking University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion