An observational study in Malignant Neoplasm, sponsored by University of Southern California. Terminated at 1 site in United States. Open to participants aged 15 Years to 39 Years. Per ClinicalTrials.gov, last updated 2025-07-25.
Sponsored by University of Southern California · Observational
This research trial studies the Adolescent and Young Adult (AYA) Cancers Clinical Model in evaluating clinical, psychosocial, and health economic factors in adolescent and young adult patients with cancer. Studying the Adolescent and Young Adult Cancers Clinical Model may help doctors learn more about the effect of the AYA services on patient care, including clinical (nurse navigation), psychosocial (social work), and economic (financial) areas.
PRIMARY OBJECTIVES:
I. To provide economic understanding of the AYA at University of Southern California (USC) model of care. (Norris)
II. To evaluate the existing AYA at USC program to determine the direct and indirect impact on cost of care. (Norris)
III. To utilize the results of objective (i) to identify cost effectiveness and efficiencies to patient and institution. (Norris)
IV. To identify specific processes within our model of care that can be improved. (Norris)
V. To improve healthcare access to AYA-specific cancer care for patients ages 15-39 served by the Los Angeles County (LAC)+USC oncology pilot clinics. (LAC+USC)
VI. To improve the psychosocial outcome of AYA-specific cancer care patients. (LAC+USC)
VII. To provide AYA specific elements of care routinely and proactively to AYA cancer patients. (LAC+USC)
VIII. To improve care quality through patient satisfaction. (LAC+USC)
IX. To improve resource utilization and care coordination through improved patient navigation through efficiency and patient navigation. (LAC+USC)
OUTLINE:
Patients complete questionnaires at referral, week 4-8, week 10-12, and at the completion of systemic therapy.
9,365 studies on the registry are indexed under Neoplasms; 2,489 are open to participants now.
This study's enrollment of 76 is below the median of 204 across 1,683 observational studies indexed under Neoplasms.
Browse Neoplasms studies →University of Southern California is the lead sponsor of 773 studies on the registry; 135 are open to participants now.
Of its 68 completed or terminated interventional studies of FDA-regulated products, 32 (47%) have results posted.
Counted across the registry records on this site, refreshed daily.
Adolescent and Young Adult (AYA) with cancer who are being seen at the USC/Norris Cancer Center and at LAC+USC Medical Center.
Exclusion Criteria:
Patients complete questionnaires at referral, week 4-8, week 10-12, and at the completion of systemic therapy.
Other: Quality-of-Life Assessment · Other: Questionnaire Administration
Ancillary studies
Also known as: Quality of Life Assessment
Ancillary studies
Clinical care model impact on patient access to AYA specific supportive care as assessed by questionnaires (Norris)
Questionnaire scores will be expressed as median values with 95% confidence intervals.
Time frame: Up to 2 years
Clinical care model impact on patient's/health care professional's satisfaction with the AYA at USC program as assessed by questionnaires (LAC+USC)
Questionnaire scores will be expressed as median values with 95% confidence intervals.
Time frame: Up to 2 years
Cost of care (Norris)
Direct health care costs analyses will be performed from the Total Costs of Care payer perspective. Direct cost will be estimated from paid claims in the extracted electronic medical records, which will include costs for all health care utilization such as outpatient, procedures, laboratory, emergency room visits, hospitalization, and pharmacy. As the healthcare utilization and costs will likely be extremely skewed, healthcare utilization and cost measures will be estimated by using an econometric model (e.g., a negative binomial regression model for utilization count data \[number of services
Time frame: Up to 2 years
Incremental cost (Norris)
The incremental cost between AYA enrolled and non-enrolled will be calculated. In addition to estimation the magnitude of the variability attributed to the different sources of variation, we will also generate an influence diagram (also known as tornado diagram) to display which variables exert the most influence on cost driver.
Time frame: Up to 2 years
Processes that can be improved (Norris)
Will utilize the prospective data to estimate key aspects of the AYA at USC service. Any variances in the services over time will be utilized to improve quality and reliability care delivery.
Time frame: Up to 2 years
Care coordination as assessed by the mean number of supportive care referrals, telephone or email encounters for additional information, educational materials, and or additional interventions provided by the nurse navigator and/or social worker (LAC+USC)
Will be measured using an implementation guide.
Time frame: Up to 2 years
Patient continuity of care as assessed by the mean number of visits per patient with the assigned clinic lead physician (LAC+USC)
Will be measured using an implementation guide.
Time frame: Up to 2 years
Resource allocation as assessed by the mean number of supportive care referrals and per patient follow-up conducted by the nurse navigator and/or social worker (LAC+USC)
Will be measured using an implementation guide.
Time frame: Up to 2 years
Satisfaction of health care staff as assessed by questionnaires (LAC+USC)
Questionnaire scores will be expressed as median values with 95% confidence intervals.
Time frame: Up to 2 years
Satisfaction of services as assessed by questionnaires (LAC+USC)
Questionnaire scores will be expressed as median values with 95% confidence intervals.
Time frame: Up to 2 years
This study is terminated, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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University of Southern California