An interventional study of Combined exercise and diet intervention in Cycling Performance, Muscular Adaptations and Substrate Utilization, sponsored by University of Aarhus. Completed. Open to male participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-10-24.
Sponsored by University of Aarhus · Not applicable, Interventional, and Other
The investigators will examine the long-term effects of a combined training and diet intervention that, acutely, increases fat oxidation during exercise. This is done with a 4 week intervention study with moderately trained cyclists. Performance is tested pre and post intervention and muscle biopsies are obtained.
University of Aarhus is the lead sponsor of 1,274 studies on the registry; 183 are open to participants now.
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Exclusion Criteria:
This subjects in this group conducts all their morning exercise sessions with high fat oxidation (in a fasted condition). Thus, the subjects in this group after high intensity exercise in the evening do not get any carbohydrates to eat after training until the exercise session the following morning has been conducted.
Other: Combined exercise and diet intervention
This subjects in this group conducts all their morning exercise sessions with low fat oxidation (in a fed condition). Thus, the subjects in this group after high intensity exercise in the evening do get carbohydrates to eat after training until the exercise session the following morning has been conducted.
Other: Combined exercise and diet intervention
Both groups exercise 6 times per week in 4 weeks conducted as 3 evening and 3 morning sessions per week. Both groups receive dietary products to be consumed immediately before and after each evening and morning session, respectively. One group conduct morning sessions in a fasted state, the other conduct the morning sessions in a fed state. Performance pre and post is measured, and muscle biopsies are obtained.
Time trial performance measured in Watts
30 min time trial after 90 minutes of intensive cycling. The average amount of Watts during the 30 minutes will be measured.
Time frame: Change from Baseline and after 4 weeks of training
Protein expression in skeletal muscle tissue
Amount of mitochondrial proteins and enzymes will be measured with a Western Blotting technique
Time frame: Baseline and after 4 weeks of training
The absolute amount of carbohydrate and fat which is metabolised during morning exercise, measured in grams/minute
Fat and carbohydrate oxidation during exercise measured and estimated with indirect calorimetry.
Time frame: Baseline and after 4 weeks of training
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Oct 2018. You cannot join it, but the record below documents what was studied.
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University of Aarhus