CClinicalTrials.gg
Status unknownNCT03014388MPMUpdated Jan 9, 2017

Posterior Maxillary Ridge Augmentation With Sinus Lift Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft

An interventional study of autogenous bone and Mineralized plasmatic matrix in Bone Resorption, sponsored by Cairo University. Status unknown. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-01-09.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Dec 2016), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
18 Years to 50 Years
Sex
All
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Study summary

Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards in sinus Lift procedures for future implant insertion.

Read the detailed description

To study the effectiveness of MPM in ridge augmentation with implant insertion compared with autogenous bone graft.

-PICO Population(P) : Patients with defective posterior maxillary alveolar ridge. Intervention (I) :Implant placement and ridge augmentation with MPM. Comparator (C) : Autogenous bone graft. Outcome (O) : Patient satisfaction - Implant stability.

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Conditions studied

  • Bone Resorption

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03

In context

Bone Resorption

153 studies on the registry are indexed under Bone Resorption; 25 are open to participants now.

This study's planned enrollment of 20 is close to the median of 22 across 133 interventional studies indexed under Bone Resorption.

Browse Bone Resorption studies →

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  1. Patients systemically free.
  2. Patients with posterior maxillary defective ridges indicated for sinus lift procedure.
  3. Cases with 5 mm bone height or less are included in the study.
  4. Age between 18 and 50 years.
  5. Both sexes.
  6. Patients physically able to tolerate surgical and restorative procedures.
  7. Good oral hygiene.
  8. Highly motivated patients.

Exclusion criteria

Exclusion Criteria:

  1. Patients allergic to local anesthetic agent.
  2. Medium and heavy smokers.
  3. Pregnant females.
  4. Presence of any pathosis in the pre-implant site.
  5. Presence of any mucosal disease.
  6. History of oral radiotherapy.
  7. History of prolonged steroids use.
  8. Psychological disorders.
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
20 participants (estimated)

Study arms

  • Experimental
    Autogenous bone graft (Gold Standard).

    Patients with defective posterior maxillary alveolar ridges requiring implant insertion will have Autogenous bone graft (Gold standard) and to be used for bone augmentation with sinus lift.

    Other: autogenous bone

  • Experimental
    Mineralized Plasmatic Matrix (MPM)

    Patients with defective posterior maxillary alveolar ridges requiring implant insertion will receive bone graft using Mineralized plasmatic matrix.

    Other: Mineralized plasmatic matrix

Interventions

  • Otherautogenous bone

    Autogenous bone graft (gold standard). sinus lift with autogenous bone.

    Also known as: Autobone

  • OtherMineralized plasmatic matrix

    By using venoud blood from the patient, together with bone graft, a centrifuge will be used to obtain the top layer after centrifuging blood at 3000 RPM.

    Also known as: MPM

06

What researchers measure

Primary outcomes

  1. Patient Satisfaction regarding aesthetic results will be measured using questionnaire.

    outcome will be measure using questionnaire.

    Time frame: 9 months

Secondary outcomes

  1. Stability of dental implants.

    will be measured using OSTELL Device.

    Time frame: 5 months

07

Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: No — Evaluation of the comparative Effectiveness of MPM Augmentation in posterior maxillary ridge defects with Autogenous bone graft.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 9, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03014388
Lead sponsor
Cairo University
Responsible party
Refaat Ragab Abu Ellill (Dentist at menistry of health, Cairo University) — Principal investigator
First posted
Jan 9, 2017
Start date
Jan 2017
Primary completion
Sep 2017 (estimated)
Completion
Oct 2017 (estimated)
Last update
Jan 9, 2017

Study contacts

refaat ragab, Master
Contact
refaat.ragab.rr@gmail.com
01111175536
Cairo University CBE
principal investigator · Cairo University - Ethics Committee.

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Dec 2016. You cannot join it, but the record below documents what was studied.

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