A Phase 4 interventional study of Tamsulosin and Placebo Oral Capsule in Postoperative Urinary Retention, sponsored by Ascension Health. Completed. Open to male participants aged 30 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-07-30.
Sponsored by Ascension Health · Phase 4, Interventional, and Prevention
Double blinded, randomized controlled prospective study looking at 2 preoperative doses of Tamsulosin an alpha-adrenergic blocker in preventing post-operative urinary retention. A previous study was conducted called "Effectiveness of tamsulosin inprevention of postoperative urinary retention: a randomized double-blind-placebo controlled study" This study involved a tertiary care center involving mostly urological surgical procedures. We look to specifically look at inguinal hernia surgeries in males. The aim of this study is to compare the prophylactic effect of tamsulosin with placebo on postoperative urinary retention. The drug is FDA approved for benign prostatic hypertrophy and urinary retention. It is on formulary at Genesys. Currently there is no standard procedure of prophylactic tamsulosin for urinary retention. Most often post operative patients are given tamsulosin to augment smooth muscle relaxation and spontaneous voiding if the patient is having urinary retention post operatively. We often straight catheterize patients once and start tamsulosin with the goal of avoiding urinary retention and future straight catheterizations or placement of foley catheters
Ascension Health is the lead sponsor of 21 studies on the registry; 3 are open to participants now.
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Exclusion Criteria:
Tamsulosin 0.4mg given the night before surgery and another dose the day of surgery in the morning.
Drug: Tamsulosin
Placebo medication given the night before surgery and another dose the day of surgery in the morning
Drug: Placebo Oral Capsule
Also known as: Flomax
number of Urinary Retention
If patients have urinary retention post operatively
Time frame: within 72 hours of surgery
placebo vs tamsulosin
Time frame: within 72 hours of surgery
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jul 2019. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Tamsulosin
Ascension Health