An interventional study of PMv stimulation (iTBS) and PMv inhibition (cTBS) in Healthy, sponsored by Centre Hospitalier St Anne. Status unknown at 1 site in France. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-04-28.
Sponsored by Centre Hospitalier St Anne · Not applicable, Interventional, and Other
The purpose of this study is determine the involvement of motor system in the memory of manipulable objects. The idea is to stimulate the ventral premotor cortex with transcranial magnetic stimulation to see whether this stimulation will affect memory of manipulable objects.
Embodied cognition claims that representations shares processing resources with sensorimotor systems. More specifically, it has been proposed that language comprehension relies on internal simulation of the meaning. For instance, numerous studies have shown that the processing of action-related concepts involve a motor activation similar to when the action is actually performed. However, even if those studies show clearly that action-related concepts involve a motor activation, such activations may be incidental to the activation of their representations, rather than part of it. Another way to show that this motor component takes part in the representation of manipulable objetcs is to investigate whether an impairment of motor system would impair the memory of manipulable object. In this study, investigators will use Transcranial Magnetic Stimulation (TMS) to stimulate ventral premotor cortex (PMv) to see whether this stimulation will affect memory of manipulable objects, but not memory of nonmanipulable objects. For this purpose, three TMS conditions will be assessed: cTBS to inhibit the motor cortex, iTBS to excite the motor cortex, and a SHAM condition as control.
Centre Hospitalier St Anne is the lead sponsor of 99 studies on the registry; 53 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
PMv stimulation (iTBS) at session 2, PMv inhibition (cTBS) at session 3, and control (SHAM) at session 4
Other: PMv stimulation (iTBS) · Other: PMv inhibition (cTBS) · Other: Control (SHAM)
PMv stimulation (iTBS) at session 2, control (SHAM) at session 3, and PMv inhibition (cTBS) at session 4
Other: PMv stimulation (iTBS) · Other: PMv inhibition (cTBS) · Other: Control (SHAM)
PMv inhibition (cTBS) at session 2, PMv stimulation (iTBS) at session 3, and control (SHAM) at session 4
Other: PMv stimulation (iTBS) · Other: PMv inhibition (cTBS) · Other: Control (SHAM)
PMv inhibition (cTBS) at session 2, control (SHAM) at session 3, and PMv stimulation (iTBS) at session 4
Other: PMv stimulation (iTBS) · Other: PMv inhibition (cTBS) · Other: Control (SHAM)
control (SHAM) at session 2, PMv stimulation (iTBS) at session 3, and PMv inhibition (cTBS) at session 4
Other: PMv stimulation (iTBS) · Other: PMv inhibition (cTBS) · Other: Control (SHAM)
control (SHAM) at session 2, PMv inhibition (cTBS) at session 3, and PMv stimulation (iTBS) at session 4
Other: PMv stimulation (iTBS) · Other: PMv inhibition (cTBS) · Other: Control (SHAM)
PMv stimulation (iTBS)
PMv inhibition (cTBS)
Control (SHAM)
Number of objects affordants and of objects not - affordants reminded
Measure of the number of objects affordants and of objects not - affordants reminded according to if the stimulation is in PMv or control
Time frame: 1 week
Number of objects affordants and of objects not - affordants reminded
Measure of the number of objects affordants and of objects not - affordants reminded according to if the stimulation is in PMv or control
Time frame: 2 weeks
Number of objects affordants and of objects not - affordants reminded
Measure of the number of objects affordants and of objects not - affordants reminded according to if the stimulation is in PMv or control
Time frame: 3 weeks
Number of object reminded
Measure of the number of objects affordants and of objects not - affordants reminded according to if the stimulation is excitation or control
Time frame: 1 week
Number of object reminded
Measure of the number of objects affordants and of objects not - affordants reminded according to if the stimulation is excitation or control
Time frame: 2 weeks
Number of object reminded
Measure of the number of objects affordants and of objects not - affordants reminded according to if the stimulation is excitation or control
Time frame: 3 weeks
Plan to share: Undecided
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This study is status unknown, as verified in Apr 2017. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier St Anne