An interventional study of Visible light exposure in Exposure to Man-made Visible Light, sponsored by University of Bern. Not yet recruiting at 1 site in Switzerland. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-01-14.
Sponsored by University of Bern · Not applicable, Interventional, and Basic science
NOTE: This is the fifth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674. This sub-study includes 50 participants and 8 arms, in total 350 participants will be assessed in all 7 sub-studies.
General study information: This is a randomized, cross-over, quantitative study, which investigates physiological variables, mood, and affect of healthy participants in response to colored light exposure. The Participants take part in 5-8 arms and are exposed to colored light only, or are additionally asked to solve cognitive tasks during the colored light exposure. Primary aim is to measure the change in several physiological variables, mood, and affect during colored light exposure of 15 or 45 minutes. The risk for the participants is negligible and comparable to the risk during daily life.
1,092 studies on the registry are indexed under Respiratory Aspiration; 216 are open to participants now.
This study's planned enrollment of 50 is above the median of 42 across 881 interventional studies indexed under Respiratory Aspiration.
Browse Respiratory Aspiration studies →University of Bern is the lead sponsor of 207 studies on the registry; 47 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
The participants will be exposed to red fluorescent light at a illuminance of 30 lux at eye level for 15 minutes. The colored light exposure will be preceded by sitting 8 minutes in darkness and followed by sitting 20 minutes in darkness.
Other: Visible light exposure
The participants will be exposed to red fluorescent light at a illuminance of 120 lux at eye level for 15 minutes. The colored light exposure will be preceded by sitting 8 minutes in darkness and followed by sitting 20 minutes in darkness.
Other: Visible light exposure
The participants will be exposed to blue fluorescent light at a illuminance of 30 lux at eye level for 15 minutes. The colored light exposure will be preceded by sitting 8 minutes in darkness and followed by sitting 20 minutes in darkness.
Other: Visible light exposure
The participants will be exposed to blue fluorescent light at a illuminance of 120 lux at eye level for 15 minutes. The colored light exposure will be preceded by sitting 8 minutes in darkness and followed by sitting 20 minutes in darkness.
Other: Visible light exposure
The participants will be exposed to green fluorescent light at a illuminance of 30 lux at eye level for 15 minutes. The colored light exposure will be preceded by sitting 8 minutes in darkness and followed by sitting 20 minutes in darkness.
Other: Visible light exposure
The participants will be exposed to green fluorescent light at a illuminance of 120 lux at eye level for 15 minutes. The colored light exposure will be preceded by sitting 8 minutes in darkness and followed by sitting 20 minutes in darkness.
Other: Visible light exposure
The participants will be exposed to white fluorescent light at a illuminance of 30 lux at eye level for 15 minutes. The colored light exposure will be preceded by sitting 8 minutes in darkness and followed by sitting 20 minutes in darkness.
Other: Visible light exposure
The participants will be exposed to white fluorescent light at a illuminance of 120 lux at eye level for 15 minutes. The colored light exposure will be preceded by sitting 8 minutes in darkness and followed by sitting 20 minutes in darkness.
Other: Visible light exposure
Subjects will be exposed to visible colored light for 15 minutes. The visible light will be generated by fluorescent light lamps.
Change in cerebral tissue oxygen saturation during colored light exposure compared with a baseline and a recovery period
Time frame: 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
Change in cerebral hemoglobin concentration during colored light exposure compared with a baseline and a recovery period
Time frame: 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
Change in variables of the heart rate variability during colored light exposure compared with a baseline and a recovery period
Time frame: 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
Change in electro-dermal activity during colored light exposure compared with a baseline and a recovery period
Time frame: 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
Change of the blood pressure during colored light exposure compared with a baseline and a recovery period
Time frame: 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
Change of the partial pressure of carbon dioxide during colored light exposure compared with a baseline and a recovery period
Time frame: 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
Change of the respiration rate during colored light exposure compared with a baseline and a recovery period
Time frame: 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
Change of the heart rate during colored light exposure compared with a baseline and a recovery period
Time frame: 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
Change of the pulse-respiratory quotient during colored light exposure compared with a baseline and a recovery period
The pulse-respiratory quotient will be calculated as heart rate divided by the respiration rate.
Time frame: 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
Change of the arterial oxygen saturation during colored light exposure compared with a baseline and a recovery period
Time frame: 43 minutes (8 min baseline, 15 min colored light exposure, 20 min recovery)
Plan to share: Undecided — Access to research data and documents will be handled according to the Manifesto to advance Data Access and Research Transparency (DART) in Switzerland, formulated at the workshop on "Improving DART in Switzerland" in Bern, November 7th, 2014.
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University of Bern