CClinicalTrials.gg
Status unknownNCT02906748Updated Sep 20, 2016

Parathyroid Auto-transplantation: Prospective Randomized Trial of the Personalized Site

An interventional study of injection with a syringe in new-site for parathyroid autografting and injection with a syringe in traditional site for parathyroid autografting in Parathyroid Autologous Transplantation, sponsored by Tongji Hospital. Status unknown at 1 site in China. Open to participants aged 10 Years to 80 Years. Per ClinicalTrials.gov, last updated 2016-09-20.

Sponsored by Tongji Hospital · Not applicable, Interventional, and Prevention

The sponsor has not verified this record recently (last verified Sep 2016), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
280
Allocation
Randomized
Ages
10 Years to 80 Years
Sex
All
01

Study summary

The functional parathyroid auto-transplantation (PA) could release parathyroid hormone (PTH) into the circulatory system of the body through the capillaries. But when parathyroid glands were auto-grafted in the sternocleidomastoid muscle, it would be inconvenient to detect PTH to examine whether the graft functions. So the investigators took the forearm as the aim place for auto-transplantation, either subcutaneous or brachioradialis, with its relatively fixed - antecubital vein blood test which is simple. The survival criteria is assumed as the PTH gradient of 1.5 times or greater through comparing the bilateral PTH value in grafted and not-grafted forearm.

02

Conditions studied

  • Parathyroid Autologous Transplantation

Keywords

  • parathyroid autografting
  • thyroidectomy
  • survival rate
  • hypoparathyroidism
03

In context

Lead sponsor

Tongji Hospital is the lead sponsor of 373 studies on the registry; 204 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
10 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • patients with indications for PA treatment during cervical surgery

Exclusion criteria

Exclusion Criteria:

  • patients suffering secondary hypoparathyroidism with forearm fistulization
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Outcomes assessor)
Enrollment
280 participants (estimated)

Study arms

  • Experimental
    new site for parathyroid auto-graft

    choose the site fairly close to the antecubital vein for parathyroid auto-transplantation

    Procedure: injection with a syringe in new-site for parathyroid autografting

  • Active comparator
    traditional parathyroid autograft

    choose not intensely close to antecubital vein for parathyroid auto-transplantation

    Procedure: injection with a syringe in traditional site for parathyroid autografting

Interventions

  • Procedureinjection with a syringe in new-site for parathyroid autografting

    new-site for parathyroid autografting, close to the antecubital vein

    Also known as: parathyroid autotransplantation, parathyroid auto-implantation, parathyroid auto-graft

  • Procedureinjection with a syringe in traditional site for parathyroid autografting

    traditional-site for parathyroid autografting,not intensively close to the antecubital vein

06

What researchers measure

Primary outcomes

  1. parahthyroid hormone gradient by comparing between grafted and non-grafted forearm

    The survival criteria is that the gradient of parathyroid hormone reaches 1.5 time or greater by comparing between grafted and non-grafted forearm

    Time frame: 1 months, 3 months and 6 months

Secondary outcomes

  1. hypoparathyroidism: parathyroid hormone less than 15pg/ml(range from 15 to 65pg/ml)

    Time frame: 6 months

07

Study locations

1 of 1 sites recruiting
  • Tongji Hospital
    Wuhan, Hubei 430030, China
    Recruiting
08

References and documents

Publications

  • Cui Q, Kong D, Li Z, Wang K, Zhang D, Tang J, Liao X, Yuan Q, Gong Y, Wu G. Parathyroid autotransplantation at a novel site for better evaluation of the grafted gland function: study protocol for a prospective, randomized controlled trial. Trials. 2019 Jan 31;20(1):96. doi: 10.1186/s13063-019-3195-9. PubMed 30704522 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 20, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02906748
Lead sponsor
Tongji Hospital
Responsible party
Gaosong Wu (Doctor, Professor, Tongji Hospital) — Principal investigator
First posted
Sep 20, 2016
Start date
Apr 2016
Primary completion
Jun 2018 (estimated)
Completion
Sep 2018 (estimated)
Last update
Sep 20, 2016

Study contacts

Gaosong Wu, PhD
Contact
wugaosongtj@163.com
0086-138-7144-4606
Gaosong Wu, PhD
study director · Department of Thyroid and Breast Surgery Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2016. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion