An interventional study of Vegetal Pole blastomer embryo and Animal Pole blastomer embryo in Preimplantation Diagnosis, sponsored by Ahmad Mustafa Mohamed Metwalley. Completed at 2 sites in 2 countries. Per ClinicalTrials.gov, last updated 2019-01-15.
Sponsored by Ahmad Mustafa Mohamed Metwalley · Not applicable, Interventional, and Supportive care
Selection of side of embryo biopsy that will not interfering with implantation power of developed blastocyst embryo during biopsy procedure arranged for PGT.
During process of embryo biopsy, it was indicated to avoid contacting cells closer to inner cell mass as it can decrease the quality of embryo and its structural composition. However, recommendation for collection from the trophectoderm (TE) side is indicated.
Absence of differentiation during cleavage-stage or morula stage at day 3 and day 4 respectively, will present the needful to focus a specific location for embryo biopsy during pre-blastocyst stages for embryo going to do genetic testing before implantation or embryo transfer.
In articulation around the second polar body or the animal pole of embryo, collection of the cell from the vegetal pole in crospondence to avoide collection form the animal pole is to be compare the results of implantation for biopsy done using the animal pole side or the random non organized biosy procedure.
Ahmad Mustafa Mohamed Metwalley is the lead sponsor of 4 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
for day 3 embryo biopsy / cleavage stage: Blastomere collection from opposite side to the 2nd polar body or from vegetal pole.
Procedure: Vegetal Pole blastomer embryo · Procedure: Animal Pole blastomer embryo
for day 3 embryo biopsy / cleavage stage: Blastomere collection from and side around the 2nd polar body and not the vegetal pole.
Procedure: Vegetal Pole blastomer embryo · Procedure: Animal Pole blastomer embryo
for day 3 embryo biopsy / cleavage stage
Also known as: Biopsy embryo from sides considered far from ICM location.
for day 3 embryo biopsy / cleavage stage
Also known as: Random biopsy without considering specific location
blastocyst location of ICM at day 5
describing the location of the inner cell mass (ICM) in location to the zona peluceda (ZP) drilling opening.
Time frame: 2 months
Implantation power
calculating the pregnancy rate for cases after biopsy.
Time frame: 2 months
Plan to share: Yes — After abstract submission or after final approval for scientific paper
The record gives a start of Jan 2015, a primary completion of Dec 2018 and a completion of Dec 2018. It does not say whether these dates are actual or estimated.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jan 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Ahmad Mustafa Mohamed Metwalley