An interventional study of Sitagliptin in Type 2 Diabetes, sponsored by Second Affiliated Hospital of Soochow University. Status unknown. Open to participants aged 40 Years to 70 Years. Per ClinicalTrials.gov, last updated 2016-09-14.
Sponsored by Second Affiliated Hospital of Soochow University · Not applicable and Interventional
The present study will recruit 9 newly diagnosed type 2 diabetic patient to receive sitagliptin 100mg daily for 12 weeks. The aim of this study was to investigate the composition of gut microbiota before and after the therapy of sitagliptin.
The present study will included 9 newly diagnosed type 2 diabetic patient to receive sitagliptin 100mg daily for 12 weeks. These patients will receive 75g oral glucose tolerance test and fasting plasma glucose levels, lipids levels, fasting insulin levels and 2 hour post-load plasma glucose levels will be measured. Stool samples will be collected before the initiation of the use of sitagliptin. After 12 weeks, all patients will have fasting plasma glucose levels, lipids levels, fasting insulin levels tested. Stool samples will be collected again.
10,925 studies on the registry are indexed under Diabetes Mellitus; 1,319 are open to participants now.
This study's planned enrollment of 9 is below the median of 80 across 8,367 interventional studies indexed under Diabetes Mellitus.
Browse Diabetes Mellitus studies →Second Affiliated Hospital of Soochow University is the lead sponsor of 60 studies on the registry; 31 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
All the patients will receive sitagliptin 100mg daily.
Drug: Sitagliptin
All the patients will receive sitagliptin 100mg daily
Also known as: Sitagliptin phosphate (Januvia; Merck)
The changes of the composition of gut microbiota before and after the use of sitagliptin
Time frame: 12 weeks
Changes of HbA1c levels
Time frame: 12 weeks
Changes of fasting plasma glucose levels, lipids levels and insulin sensitivity
Time frame: 12 weeks
No study locations are listed for this record.
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Sep 2016. You cannot join it, but the record below documents what was studied.
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Second Affiliated Hospital of Soochow University