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CompletedNCT02894827MEDICANUT2Updated Sep 9, 2016

The Effect of When Medication is Taken on Nutritional Status in Hospitalized Patients Older Than 65 Years

An observational study in Nutritional Status, sponsored by Centre Hospitalier Universitaire Dijon. Completed at 1 site in France. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2016-09-09.

Sponsored by Centre Hospitalier Universitaire Dijon · Observational

Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
30
Ages
65 Years and older
Sex
All
01

Study summary

Polypathology in elderly subjects requires polypharmacy but even though the efficacy of a medication and digestive tolerance are ensured, the medication can be taken a long time from meals to reduce its side-effects. Despite numerous studies that have investigated links between medication and malnutrition, none have assessed the influence of the time the drug is taken on the evolution of the nutritional status of elderly hospitalized persons. So as to identify the best nutritional criterion in hospitalized persons, a retrospective pilot study will be conducted in about thirty patients. Their medication will be recorded and their nutritional status will be evaluated using the Geriatric Nutritional Risk Index (GNRI), albumin, prealbumin levels, weight and the Mini Nutritional Assessment (MNA) short form.

This preliminary study will allow us to choose the best nutritional criterion to compare the impact of two strategies for taking medication (post prandial versus pre-prandial) on improving the nutritional status of malnourished elderly hospitalized patients taking multiple drugs.

02

Conditions studied

  • Nutritional Status
03

In context

Lead sponsor

Centre Hospitalier Universitaire Dijon is the lead sponsor of 495 studies on the registry; 105 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
65 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patients with a stable or controlled acute disease hospitalized in a geriatric follow-up care unit

Inclusion criteria

  • patients aged 65 years or more.
  • patients with a stable or controlled acute disease hospitalized in a geriatric follow-up care unit.
  • patients whose life expectancy is greater than 30 days.
  • patients able to eat food normally.
  • patients able to swallow their medication.
  • patients with at least 3 drugs to be taken orally per day, not including oral nutritional supplements.

Exclusion criteria

Exclusion Criteria:

  • patients at the end of life.
  • patients whose drugs must be taken before meals like Non-steroid anti-inflammatory drugs (NSAIDs), glinides, oral antidiabetic agents (OAD).
  • patients with parenteral and/or enteral nutrition in the period preceding admission to the geriatric unit.
  • patients with indications for parental and/or enteral nutrition.
05

Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
30 participants (actual)
Patient registry
No

Groups and cohorts

  • EMS

    Biological: Blood sample · Other: Flow cytometry · Other: western blot

  • Control

    Biological: Blood sample · Other: Flow cytometry · Other: western blot

Interventions

  • BiologicalBlood sample
  • OtherFlow cytometry
  • Otherwestern blot
06

What researchers measure

Primary outcomes

  1. MNA short form

    Time frame: 30 days

Secondary outcomes

  1. Geriatric Nutritional risk form

    Time frame: 30 days

07

Study locations

1 site
  • CHU Dijon Bourgogne
    Dijon, 21079, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 9, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02894827
Lead sponsor
Centre Hospitalier Universitaire Dijon
Responsible party
Sponsor
First posted
Sep 9, 2016
Primary completion
Sep 2015
Last update
Sep 9, 2016
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2016. You cannot join it, but the record below documents what was studied.

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