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CompletedNCT02876627Updated Aug 24, 2016

Effect Aerobic Training on Women With Breast Cancer After Chemotherapy

A Phase 1 interventional study of Exercise training in Cancer, Exercise and Hemoglobins, sponsored by University of Isfahan. Completed. Open to female participants aged 47 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-08-24.

Sponsored by University of Isfahan · Phase 1, Interventional, and Treatment

Phase
Phase 1
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
47 Years to 65 Years
Sex
Female
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Study summary

Introduction: The purpose of this study was to determine the effect of twelve weeks of aerobic exercise program on erythrocyte levels in women with breast cancer after chemotherapy.

Methods: Thirty women with breast cancer after chemotherapy of Sydalshhda hospital (aged between 47-65 years) volunteered for this study, and then randomly selected an exercise (n = 15) and control (n = 15) groups. Exercise group completed a twelve-week aerobic exercise training program consisted of three sessions per week, each session lasting 30 to 60 minutes 50 to 75 percent of their maximum heart rate reserve, while the control group were followed. Blood samples including red blood cell counts (RBC), hematocrit (HCT), hemoglobin (HB), peak oxygen consumption before and after 12 weeks of aerobic exercise were measured. For analysis of data, repeated-measures analysis of variance (ANOVA) was used.

02

Conditions studied

  • Cancer
  • Exercise
  • Hemoglobins
03

In context

Lead sponsor

University of Isfahan is the lead sponsor of 4 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
47 Years to 65 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

women with breast cancer , who can do a physical, physiological and psychological test; and did not have exercise limitations due to neuromuscular and/or musculoskeletal disease; did not have any health problems that prevented maximum effort on the treadmill test.

Exclusion criteria

Exclusion Criteria:

women under erythropoietin treatments, uncontrolled cardiovascular or pulmonary diseases, uncontrolled arrhythmias, orthopedic conditions that would limit exercise participation, refusal for randomization, or participation in aerobic exercise training within 3 months before beginning the study.

05

Study design

Phase
Phase 1
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    breast cancer

    Effect of exercise training on breast cancer patient

    Behavioral: Exercise training

Interventions

  • BehavioralExercise training

    twelve-week aerobic exercise training program consisted of three sessions per week, each session lasting 30 to 60 minutes 50 to 75 percent of their maximum heart rate reserve

06

What researchers measure

Primary outcomes

  1. effect of exercise on CBC parameters (measured by ELISA methods)

    Time frame: up to 12 weeks

Secondary outcomes

  1. effect of exercise on peak oxygen consumption, measured by vo2 max test

    Time frame: up to 12 weeks

07

Study locations

No study locations are listed for this record.

08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 24, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02876627
Lead sponsor
University of Isfahan
Responsible party
Prof.Mehdi Kargarfard (Principal Investigator, University of Isfahan) — Principal investigator
First posted
Aug 24, 2016
Start date
Feb 2015
Primary completion
Jun 2015
Completion
Apr 2016
Last update
Aug 24, 2016
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Aug 2016. You cannot join it, but the record below documents what was studied.

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