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CompletedNCT02873533MEGERIAUpdated Sep 30, 2025

Modification of the Quality of Life Based on Objective Geriatric Tests

An interventional study of geriatric care and longitudinal follow up in Cancer and Elderly Patients, sponsored by Centre Antoine Lacassagne. Completed at 1 site in France. Open to participants aged 70 Years and older. Per ClinicalTrials.gov, last updated 2025-09-30.

Sponsored by Centre Antoine Lacassagne · Not applicable, Interventional, and Supportive care

Phase
Not applicable
Study type
Interventional
Enrollment
76
Allocation
Not applicable
Ages
70 Years and older
Sex
All
01

Study summary

The analysis of this study will achieve an improvement in the management of patients over 70 years with adaptation of chemotherapy regimens after analysis of the subject and its psychosocial environment.

The analysis of socio-economic impacts will implement actions to optimize the care of the elderly while emphasizing the value of management / cost of care.

Read the detailed description

Quality of life is defined as "an individual's perception of his place in life, in the context of culture and value system in which he lives, in relation to its goals, expectations, standards and concerns "(WHO 1993).

This concept refers to multiple dimensions, both objective and subjective:

  • The physical condition of the person, his functional abilities;
  • His somatic sensations;
  • His psychological health;
  • His social status, relational environment.

This concept focuses on perception's basics. Quality of life is a criteria supposed to be objective even though it is subject to subjective interpretation at the highest point. Indeed, if the quality of life varies depending on the discretion of each person, it also changes over time: it refers to a situation at a given moment and not to a stable state.

Therefore in this study, it seemed appropriate to show the concept of "quality of life objective" which is linked to objective data measures recognized criteria for evaluating the elderly. These criteria are repeatable, validated and not dependent operator.

This process completely matches with the actions promoted by the 2009-2013 Cancer Plan (measures 23 and 26) on the basis of an improvement of:

  • The quality of consideration of the psychosocial dimension (customization accompaniment, living environment, social, involvement, ..)
  • The quality of the integration of physical and psychological dangers inherent to this weakness situation induced by cancer.
02

Conditions studied

  • Cancer
  • Elderly Patients

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03

In context

Neoplasms

9,365 studies on the registry are indexed under Neoplasms; 2,489 are open to participants now.

This study's enrollment of 76 is above the median of 50 across 7,253 interventional studies indexed under Neoplasms.

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Lead sponsor

Centre Antoine Lacassagne is the lead sponsor of 65 studies on the registry; 15 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
70 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patient over 70 years,
  • Patient with a solid malignant tumor,
  • Patients for whom a first line chemotherapy is theoretically indicated
  • Patient chemotherapy naive,
  • Performance Index (PS) \<4

Exclusion criteria

Exclusion Criteria:

  • Patient not understanding or do not speak French,
  • Patients with any severe psychopathological disorder preventing the completion of the questionnaire or invalidating a priori measures of the questionnaire
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
76 participants (actual)

Study arms

  • Other
    A-Elderly patients with cancer

    geriatric care and longitudinal follow up

    Other: geriatric care and longitudinal follow up

Interventions

  • Othergeriatric care and longitudinal follow up

    geriatric care and longitudinal follow up

06

What researchers measure

Primary outcomes

  1. Measuring quality of life according to geriatric questionnaires

    Activities of Daily Living Questionnaire

    Time frame: 36 months

Secondary outcomes

  1. Geriatric Screening Test fragilities and comorbidities

    Mini Mental State Examination

    Time frame: 36 months

07

Study locations

1 site
  • Centre Antoine LACASSAGNE
    Nice, 06189, France
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 30, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02873533
Lead sponsor
Centre Antoine Lacassagne
Responsible party
Sponsor
First posted
Aug 19, 2016
Start date
Mar 2013
Primary completion
Mar 2019
Completion
Apr 1, 2019
Last update
Sep 30, 2025

Study contacts

Véronique MARI, md
principal investigator · Centre Antoine Lacassagne

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2018. You cannot join it, but the record below documents what was studied.

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