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CompletedNCT02862795PAPILLANUpdated Aug 11, 2016

Human Papillomavirus Anal Infection

An interventional study of HPV detection in anal canal samples in HPV Infection, sponsored by Centre Hospitalier Universitaire de Besancon. Completed at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-08-11.

Sponsored by Centre Hospitalier Universitaire de Besancon · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
500
Allocation
Not applicable
Ages
18 Years and older
Sex
All
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Study summary

Human papillomavirus (HPV) are involved in up to 95 % of anal canal neoplastic lesions. Little is known about HPV carriage in anal canal previous to cancer occurrence in the population and pre-neoplastic lesions, and their risk factors. PAPILLAN is a prospective study that aims to study HPV infection (HPV low grade and high grade genotypes) prevalence in anal canal in a population non selected by its HIV status. In that purpose patients are prospectively recruited in a french university hospital gastroenterology unit and anal smears are collected during a colonoscopy with cytobrush.

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Conditions studied

  • HPV Infection

Keywords

  • colonoscopy
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In context

Infections

6,687 studies on the registry are indexed under Infections; 807 are open to participants now.

This study's enrollment of 500 is above the median of 120 across 4,200 interventional studies indexed under Infections.

Browse Infections studies →

Lead sponsor

Centre Hospitalier Universitaire de Besancon is the lead sponsor of 439 studies on the registry; 97 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • patients > 18 years
  • patients undergoing colonoscopy under general anesthesia for any purpose
  • signed written consent

Exclusion criteria

Exclusion Criteria:

  • age under 18
  • Absence of written consent.
  • patients incapable of giving consent
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Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
500 participants (actual)

Study arms

  • Other
    HPV detection in anal canal samples

    Procedure: HPV detection in anal canal samples

Interventions

  • ProcedureHPV detection in anal canal samples

    Additional anal taking during the colonoscopy with cytobrush

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What researchers measure

Primary outcomes

  1. anal canal HPV infection

    Time frame: at inclusion (the day of colonoscopy)

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Study locations

2 sites
  • Centre Hospitalier Régional Universitaire de Besançon
    Besançon, 25030, France
  • Centre Hospitalier Intercommunal de la Haute Saône
    Vesoul, 70014, France
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 11, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02862795
Lead sponsor
Centre Hospitalier Universitaire de Besancon
Responsible party
Sponsor
First posted
Aug 11, 2016
Start date
Apr 2012
Primary completion
Jun 2016
Completion
Jun 2016
Last update
Aug 11, 2016

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2016. You cannot join it, but the record below documents what was studied.

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