An observational study in Acute Circulatory Failure During One-lung Ventilation Surgery, sponsored by Assistance Publique Hopitaux De Marseille. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-08-08.
Sponsored by Assistance Publique Hopitaux De Marseille · Observational
During thoracic surgery, an excessive use of fluid results in pulmonary complications. Dynamic fluid responsiveness predictors are not easily usable during one lung ventilation. The investigators hypothesized that the assessment by transesophageal echocardiography (TEE) of subaortic velocity time index (VTI) variation after 100 ml of crystalloid would predict fluid responsiveness in patients receiving one-lung ventilation.
This retrospective, observational, single center study was from January 2014 to December 2015. The investigators included 105 patients requiring one lung ventilation lung resection. The investigators analysed 39 patients presenting an acute circulatory failure. 100 ml of crystalloid was infused over 1-min. After an echocardiographic assessment at 1-min, remaining 400 ml were administered over 14-min Fluid responsiveness was defined as an increase in the VTI above 15% after infusion of 500 ml of crystalloid.
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Patients requiring one lung ventilation lung resection.
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Exclusion Criteria:
patients requiring one lung ventilation lung resection.
Other: Fluid challenge · Other: Trans-oesophageal echography
100 ml of crystalloid was infused over 1-min
an echocardiographic assessment at 1-min,
Fluid responsiveness
increase of cardiac output of more than 15%
Time frame: one day
Velocity time index
: Echographic assesment of cardiac output
Time frame: one day
Pulsed pressure variation
dynamic indice of fluid responsiveness
Time frame: one day
The record gives a start of Jan 2014, a primary completion of Dec 2015 and a completion of Aug 2016. It does not say whether these dates are actual or estimated.
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This study is completed, as verified in Aug 2016. You cannot join it, but the record below documents what was studied.
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