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CompletedNCT02850757Updated Jan 25, 2018

Comparison Between Modified William's Airway and U Shaped Guedl's Airway

An interventional study of U shaped Guedl's airway and Modified William's airway in Endotracheal Intubation, sponsored by Cairo University. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-01-25.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

This study will compare the efficacy of modified William's airway versus U shaped Guedl's airway in assistant of fiberoptic bronchoscope during endotracheal intubation

Read the detailed description

Several oropharyngeal airways and supraglotic devices have been invented to facilitate the art of fiber optic intubation. The oropharyngeal airways help during fiber optic intubation through raising the soft palate and the tongue away from the field of bronchoscope .(1)The modification made to the Williams airway (Fekry's airway) is that the roof of the proximal cylindrical tunnel was removed and opened from its concave part to allow one step insertion of the tube. There is no need for removal of the tube connector or the airway after tube insertion.(3)We invented a new modification in Guedel's airway (The U-shaped Guedel's airway) which is made by making an inverted Y shape cut in the roof of the airway keeping only the proximal Y wings and removing the distal part of the roof.This study will be conducted at Kasr AL-Ainy Hospital Faculty of Medicine Cairo university Egypt , after approval of the ethical committee and taking written informed consents from the patients . Patients presents to the hospital for elective surgery under general anasethia will be randomly divided into 2 groups : Group W (Gw)(n=25 ) the fiber optic intubation will be assisting by modified Williams airway and Group U (Gu)(n=25) the fiber optic intubation will be assisting by U shaped Guedels airway .

In the preparation room 20 guage cannula will be inserted in a peripheral vein . 0,02 mg\ Kg midazolam and 0,01 mg\Kg atropine will be given in the operating room Standard monitors ( ECG, noninvasive Blood pressure and pulse oximetry) will be established to the patient .After 3 minutes preoxygenation with 100% O2 induction was conducted using 1µg\Kg fentanyl,2mg\Kg propofol and 0.05 mg\Kg atracurium. After loss of consciousness the selected airway according to group randomization was inserted into the mouth (size selection and technique of insertion was done according to manufacturer structures . The patient will be ventilated by facemask and bag with 100% oxygen and 1-2% isoflourane. Complete neuromuscular block was confirmed using nerve stimulator (train of four zero).the fiber optic bronchoscope inserted through the airway (modified Williams, U Shaped Guedels airway ) according to the patient group . The time of fiber optic bronchoscope insertion will be recorded in seconds (defined as the time elapsing from the entry of fiber optic bronchoscope through the airway till touching the vocal cords by the tip of bronchoscope) . The investigator will assesse the bronchoscopic view just after the end of the airway . after recording the time of fiberopticbronchoscope insertion the endotracheal tube was slided through vocal cords into the trachea reaching the carina . the patient will be ventilated through the endotracheal tube using intermittent positive pressure ventilation (IPPV) . Endotracheal intubation will be confirmed by chest expansion ,bilateral equal air entry using stethoscope and the appearance 6 successive capnographic waves. Time of intubation will be recorded from stop mask-bag ventilation till reventilate the patient using the endotrachealtube and reading of capnogram. ( the attempt will be cancelled and bag-mask ventilation started if SPO2 reach 93%. )

02

Conditions studied

  • Endotracheal Intubation

Keywords

  • Modified William's airway
  • fiberoptic bronchoscope
  • U shape Guedls airway
  • oral airways
  • efficacy and safety
03

In context

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patient aged above 18 years old.
  • Patient that has ASA I,II .
  • Patient with Ganzouri airway score less than 4.

Exclusion criteria

Exclusion Criteria:

  • Patient aged below 18 years old.
  • Patient that has ASA III ,IV.
  • Patients at risk of aspiration of gastric content.
  • Patient with Ganzouri airway score equal or more than 4.
  • Patient that has any anatomical abnormality that invalidate Ganzouri airway score.
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Single group
Masking
Single (Participant)
Enrollment
50 participants (actual)

Study arms

  • Experimental
    U shaped Guedl's airway

    Device: U shaped Guedl's airway

  • Experimental
    Modified William's airway(Fekry airway )

    Device: Modified William's airway

Interventions

  • DeviceU shaped Guedl's airway

    To use U shaped Guedl's airway for assisting fiberoptic bronchoscope during endotracheal intubation

  • DeviceModified William's airway

    Use Modified William's airway for assisting fiberoptic bronchoscope dduring endo tracheal intubation

    Also known as: Fekry airway

06

What researchers measure

Primary outcomes

  1. Time of endotracheal intubation

    Time frame: within 15 minutes from induction of general anesthesia

Secondary outcomes

  1. Time of fiberopticc bronchscpe reach the vocal cords

    Time frame: within 15 minutes from induction of general anesthesia

  2. Bronchoscopic view grade

    Time frame: within 15 minutes from induction of general anesthesia

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 25, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02850757
Lead sponsor
Cairo University
Responsible party
Sherin Refaat (lecturer of Anasethiology and pain managment, Cairo University) — Principal investigator
First posted
Aug 1, 2016
Start date
Aug 2016
Primary completion
Dec 1, 2016
Completion
Dec 20, 2016
Last update
Jan 25, 2018

Study contacts

Maha My youssef, consultant
principal investigator · Kasr alaini hospital,faculty of medicine,cairo university

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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