An interventional study of Stevia rebaudiana liquid extract in Diabetes Mellitus, sponsored by Yaounde Central Hospital. Completed at 1 site in Cameroon. Open to participants aged 21 Years to 75 Years. Per ClinicalTrials.gov, last updated 2017-01-24.
Sponsored by Yaounde Central Hospital · Not applicable, Interventional, and Treatment
The main aim of the study is to assess the short term and 1-month metabolic effects of Stevia rebaudiana bertoni in patients with type 2 diabetes.
This is a non-randomized clinical trial in a type 2 diabetic population aiming to investigate the effect of Stevia rebaudiana bertoni on the glycaemic and insulin secretory response to a mixed meal tolerance test, insulin sensitivity and lipid profile. The study has two arms including an intervention arm (test group) and a non-intervention arm (controls) matched for age, sex and body mass index in 2:1 ratio.
The intervention is made of two phases including
10,925 studies on the registry are indexed under Diabetes Mellitus; 1,319 are open to participants now.
This study's enrollment of 22 is below the median of 80 across 8,367 interventional studies indexed under Diabetes Mellitus.
Browse Diabetes Mellitus studies →Yaounde Central Hospital is the lead sponsor of 22 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Once-daily oral intake of 240 mg of Stevia liquid extract for 30 days as food supplement.
Dietary Supplement: Stevia rebaudiana liquid extract
No intervention, similar follow up as experimental arm to control for trial effect
Sweetener made of liquid stevia self administered daily for 30 days
Glycaemic profile in response to mixed meal test
Change in blood glucose profile during a mixed meal test at baseline and after one month intervention
Time frame: 1 month
insulin secretion in response to mixed meal test
Change in serum C-peptide profile during a mixed meal test at baseline and after one month intervention
Time frame: 1 month
Serum lipids
Change in fasting serum lipids
Time frame: 1 month
Insulin sensitivity
Change in mixed meal derived insulin sensitivity
Time frame: 1 month
Liver enzymes
Change in serum alanine amino transferase
Time frame: 1 month
This study is completed, as verified in Jan 2017. You cannot join it, but the record below documents what was studied.
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Yaounde Central Hospital