An interventional study of cast immobilization group and complete sport rest. in Osgood Schlatter Disease, sponsored by Hospices Civils de Lyon. Completed at 1 site in France. Open to participants aged 9 Years to 15 Years. Per ClinicalTrials.gov, last updated 2025-12-19.
Sponsored by Hospices Civils de Lyon · Not applicable, Interventional, and Treatment
The disease Osgood-Schlatter is most commonly found in sports teenager growing up apophysose accounting for 28.4% of osteochondrosis by Breck. It relates to 62% of osteochondrosis knee and affects adolescent girls between 10 and 12 and boys between 12 and 15 It is usually considered a benign pathology that cures in the majority of cases. However, in 5-10% of cases there is persistent residual pain in adulthood.
The classic complication is the avulsion fracture of the tibial tuberosity in adolescents who continued his sports without restriction.
The possible consequences are numerous including the presence of a free bone fragment at the insertion of the tendon originally described by Osgood the establishment of a genu recurvatum, a high kneecap or patella alta and an enlarged tibial tuberosity (ATT) annoying sport.
The main two treatments are complete rest from sport activity or cast immobilization.
The main objective is to compare these two technics according to the proportion of full sporting recovering at 12 months
16 studies on the registry are indexed under Osteochondrosis; 5 are open to participants now.
This study's enrollment of 72 is above the median of 51 across 13 interventional studies indexed under Osteochondrosis.
Browse Osteochondrosis studies →Hospices Civils de Lyon is the lead sponsor of 1,866 studies on the registry; 448 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
36 patients in the experimental cast immobilization
Other: cast immobilization group
36 patients in the complete sport rest group
Other: complete sport rest.
Patients in this group will have their knee locked with a resin going from the ankle to the top of the thigh for 4 weeks, followed by 4 weeks without cast but with rehabilitation through physiotherapy.
Patients included in this group will follow the current standard procedure for this disease that is to say complete sport rest during 8 weeks including rehabilitation through physiotherapy, following the exact same technic as the experimental group .
Restarting a sporting activity
Comparison between the 2 groups of the proportion of patient returning to sports activity 12 weeks after treatment.
Time frame: 12 weeks after intervention
Anterior tibial tuberosity pain
Mean pain evaluation using Visual analogic scale between the 2 groups, at Anterior tibial tuberosity palpation
Time frame: Inclusion visit Day 0
Anterior tibial tuberosity pain
Mean pain evaluation using Visual analogic scale between the 2 groups, at Anterior tibial tuberosity palpation
Time frame: follow-up visit week 4
Anterior tibial tuberosity pain
Mean pain evaluation using Visual analogic scale between the 2 groups, at Anterior tibial tuberosity palpation
Time frame: follow-up visit week 8
Anterior tibial tuberosity pain
Mean pain evaluation using Visual analogic scale between the 2 groups, at Anterior tibial tuberosity palpation
Time frame: follow-up visit week 12
Pain killer consumption
Evaluation of pain killer consumption (type, dose ,frequency) between the 2 groups
Time frame: follow-up visit week 4
Pain killer consumption
Evaluation of pain killer consumption (type, dose ,frequency) between the 2 groups
Time frame: follow-up visit week 8
Quality of life assessment
Quality of life will be assessed using the SF-12 auto questionnaire
Time frame: inclusion visit Day 0
Quality of life assessment
Quality of life will be assessed using the SF-12 auto questionnaire
Time frame: follow-up visit week 12
Quality of life assessment
Quality of life will be assessed using the SF-12 auto questionnaire. As the standard follow-up visit are over, this questionnaire will be asked by phone
Time frame: follow-up visit month 6
Activity level assessment
Activity level will be assessed using the Tegner scale
Time frame: inclusion visit Day 0
Activity level assessment
Activity level will be assessed using the Tegner scale
Time frame: follow-up visit week 12
Activity level assessment
Activity level will be assessed using the Tegner scale. As the standard follow-up visit are over, this scale will be asked by phone
Time frame: follow-up visit month 6
complete sport rest compliance assessment
The complete sport rest compliance will be assessed using a visual analogic scale (0 to 10, 0 will be a complete rest compliance)
Time frame: follow-up visit week 4
painfulness due to immobilization cast
The patient in the cast immobilization group will be asked what was the level his/her level of cast tolerance: bad, average, good or very good.
Time frame: follow-up visit week 12
Quadricipital shortness
The Quadricipital shortness will be evaluated thanks to the knee flexion angle will be measured using the modified Thomas test as well as hamstring muscles length measured using the popliteal angle
Time frame: inclusion visit Day 0
Quadricipital shortness
The Quadricipital shortness will be evaluated thanks to the knee flexion angle will be measured using the modified Thomas test as well as hamstring muscles length measured using the popliteal angle
Time frame: follow-up visit week 4
Quadricipital shortness
The Quadricipital shortness will be evaluated thanks to the knee flexion angle will be measured using the modified Thomas test as well as hamstring muscles length measured using the popliteal angle
Time frame: follow-up visit week 8
Patella size
The patella size will be measure on the lateral radiograph using the Caton and Deschamp index
Time frame: inclusion visit Day 0
Patella size
The patella size will be measure on the lateral radiograph using the Caton and Deschamp index
Time frame: follow-up visit week 8
Radiographic evolution of Osgood Schlatter disease
Both clinicians and radiologist will evaluate separately the evolution of Osgood Schlatter disease using a new classification. It is based on 3 parameters: anterior tibial tuberosity fragmentation, thickening of soft tissues and presence or not of an ossicle.
Time frame: follow-up visit week 12
Potential return to sport activity
After a week of training, patients of each group will be evaluated and the clinician will consider the possibility of a potential return to sport activity the week 8 of follow-up
Time frame: follow visit week 8
Return to sport activity at the initial level
Six months after the intervention, patients will be called to evaluate if they were able to return to a sport activity at the same level they were before the disease. This proportion will be compared in between both groups
Time frame: follow visit month 6
alternative options during the study
Each patient will be ask during the phone interview at 6 months if the consulted another physicians or if they used an alternative to that proposed in our study.
Time frame: follow visit month 6
Ran from Sep 2015 to primary completion in Dec 2016, 15 months.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.