An observational study in Diabetes Mellitus, Type 2, sponsored by Fourth People's Hospital of Shenyang. Completed. Open to participants aged 34 Years to 68 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-05-17.
Sponsored by Fourth People's Hospital of Shenyang · Observational
Objective: The main target of this study was to research the correlation between the pulmonary function and the circulatory parameters of retrobulbar blood vessels in patients with type 2 diabetes (T2DM) without diabetic retinopathy (DR).
Method: T2DM patients without DR were choose to research the correlation between the pulmonary function and the circulatory parameters of retrobulbar blood vessels. The primary endpoints were the pulmonary function parameters; The secondary endpoints were the HbA1c, FPG, 2hPG, WC, and BMI. The tertiary endpoints were the blood-fat; In addition, the retrobulbar circulation in the retrobulbar blood vessels were evaluated using color doppler imaging (CDI).
Pulmonary function parameters (VC%, FVC%, FEV1%, PEF%, MVV%, TLC%, FEV1/FVC%, DLCO%, and DLCO/VA%); the retrobulbar circulation (PSV, EDV, RI);retrobulbar blood vessels (CRA, PCA, and OA);blood-fat(TC, HDL-C, LDL-C, and TG).
Pulmonary function was measured by spirometer which was provided by Jaska Corporation in Japan, model number: HI-101; The CDI recordings were taken using a Powervision SSA-380A (Toshiba, Japan) using a 7-MHz transducer.
9,359 studies on the registry are indexed under Diabetes Mellitus, Type 2; 1,318 are open to participants now.
This study's enrollment of 48 is below the median of 300 across 1,588 observational studies indexed under Diabetes Mellitus, Type 2.
Browse Diabetes Mellitus, Type 2 studies →Fourth People's Hospital of Shenyang is the lead sponsor of 4 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Investigators selected 60 patients (34 males, 26 females) with T2DM from the the diabetic outpatient clinic in Shenyang the Fourth Hospital of People, but only 48 patients (26 males, 22 females) can be researched in our study. All patients were provided a diet and exercise program by professional nutritionists. The race ratio (all were Chinese Hans), age (range from 34 to 68 years), diabetes duration (range from 3 to 12 years), BMI (range from 20 to 30 kg/m2), HbA1c [ range from 7.0 % (53 mmol/mol) to 10 % (86 mmol/mol) ]. Through the detecting, we excluded 6 patients (4 were in A1 stage, 2 was in A2 stage) because of DR. Finally, 48 patients (26 males, 22 females) completed the study.
Exclusion Criteria:
The pulmonary function (using spirometer)of three categories of patients, based on HbA1c levels, were compared
pulmonary function parameters include: VC%, FVC%, FEV1%, PEF%, MVV%, TLC%, FEV1/FVC%, DLCO%, and DLCO/VA%;HbA1c levels: ≥ 8.0, \< 8.0 and \> 7.0, ≤ 7.0
Time frame: one week
The circulatory parameters (using CDI)of retrobulbar blood vessels of three categories of patients, based on HbA1c levels, were compared
retrobulbar blood vessels include CRA, PCA, and OA; circulatory parameters include PSV, EDV, and RI; HbA1c levels: ≥ 8.0, \< 8.0 and \> 7.0, ≤ 7.0
Time frame: one week
The correlation between the pulmonary function parameters and the retrobulbar circulation parameters in 48 T2DM patients
Time frame: one week
HbA1c, FPG, 2hPG, WC,BMI, DBP, SBP, and blood-fat in 48 T2DM patients
blood-fat include TC, HDL-C, LDL-C, and TG
Time frame: one week
No study locations are listed for this record.
This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.
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Fourth People's Hospital of Shenyang