An observational study in Diabetes, Gestational, sponsored by University of Aarhus. Completed at 1 site in Denmark. Open to female participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-09-27.
Sponsored by University of Aarhus · Observational
Aim of the study:
To define insulin requirement during pregnancy and to identify the rapid changes in insulin sensitivity around parturition and the first 6 months post partum. Such knowledge would be clinically useful and markedly improve insulin treatment before and after parturition for women with type 1 diabetes and serve to identify the best possible timing of testing women with gestational diabetes mellitus (GDM) for the development of type 2 diabetes post partum.
Method:
Botnia clamp in women before, immediately after delivery and 6 months post partum. The investigators will compare 20 women with GDM in late pregnancy, day 15 post partum and 6 months post partum with 20 normal women investigated at the same time points. In addition the investigators will collect feces samples from the mother and baby in order to determine microbiota.
Perspectives:
Diabetes is a common condition with important implications for pregnancy outcome and long-term morbidity for mother and offspring. Accordingly, tailoring the best treatment is expected to have beneficial consequences both for the pregnant women and the future generation.
842 studies on the registry are indexed under Diabetes, Gestational; 198 are open to participants now.
This study's enrollment of 10 is below the median of 200 across 269 observational studies indexed under Diabetes, Gestational.
Browse Diabetes, Gestational studies →University of Aarhus is the lead sponsor of 1,274 studies on the registry; 183 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All women visiting the outpatient gestational diabetes clinic at Aarhus University Hospital will be approached.
Exclusion Criteria:
10 women with gestational diabetes
Change in insulin sensitivity
Performing a Botnia clamp 3 times around parturition on women with GDM and comparing them with women with no GDM. The women will be their own control prospectively but also compared with a control group without gestational diabetes in order to compared them cross sectionally
Time frame: Determined one time between gestational week 32 to 37, 14 days postpartum and 6 months postpartum.
Changes in the microbiota
Investigators will ask the participants to bring feces samples from themselves and their baby.
Time frame: Determined one time between gestational week 32 to 37 (only the mother), 14 days postpartum and 6 months postpartum.
This study is completed, as verified in Sep 2019. You cannot join it, but the record below documents what was studied.
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University of Aarhus