An interventional study of Laparoscopic endoscopy combined surgery and laparoscopic and endoscopic cooperative surgery in Gastrointestinal Stromal Tumor, sponsored by First Affiliated Hospital Xi'an Jiaotong University. Status unknown at 1 site in China. Per ClinicalTrials.gov, last updated 2018-02-07.
Sponsored by First Affiliated Hospital Xi'an Jiaotong University · Not applicable, Interventional, and Treatment
Gastric stromal tumor is a gastrointestinal mesenchymal tumor with malignant differentiation potential, the incidence increased year by year. The surgical resection is the primary treatment for it. Although laparoscopic GIST resection has many benefits,due to in lack of the delicate sense of touch, it could lead to the incomplete resection and disorders of digestion. More than 33% of postoperative patients have the gastric dysfunction. Laparoscopic endoscopy combined surgery is different from the past technology. It is a new radical resection of GIST presented by Japanese scholars. LECS resects the tumor completely by laparoscopy with the help of the precise positioning and guidance of endoscopy .This method conforms to the idea of the modern minimally invasive surgery, and avoids many problems,such as incomplete resection and disorders of digestion caused by excessive tissue resection. our team will spearhead the GIST treatment of LECS. First of all, the investigators will collect 120 cases of GIST patients, randomly assigned for the laparoscopic group, the LECS, single-arch the LECS surgical treatment. Secondly, to analyzing the basic treatment and follow-up data, including the operation time, blood loss, the number of transfer laparotomy, the number of cut edge positive, the distances of cut edge away from the tumor edge, the cases of anastomotic fistula bleeding, stenosis, average such confinement, the meal time, cost of treatment, tumor recurrence rate, the presence of residual stomach, upset stomach and frequency, reflux esophagitis, bile reflux gastritis and other indicators.The purpose of this subject is to observe the effectivity and safety of LECS and single-arch the LECS, invent serval LECS equipment patents and provide some references for LECS applying to the minimally invasive surgery of the digestive tract tumor and multidisciplinary treatment mode .
333 studies on the registry are indexed under Gastrointestinal Stromal Tumors; 61 are open to participants now.
This study's planned enrollment of 120 is above the median of 50 across 243 interventional studies indexed under Gastrointestinal Stromal Tumors.
Browse Gastrointestinal Stromal Tumors studies →First Affiliated Hospital Xi'an Jiaotong University is the lead sponsor of 306 studies on the registry; 86 are open to participants now.
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Exclusion Criteria:
Laparoscopic endoscopy combined surgery. This is a kind of traditional surgical method.
Procedure: Laparoscopic endoscopy combined surgery
LECS resects the tumor completely by laparoscopy with the help of the precise positioning and guidance of endoscopy .
Procedure: laparoscopic and endoscopic cooperative surgery
Single-arch LECS resects the tumor completely by laparoscopy with the help of the precise positioning and guidance of endoscopy
Procedure: Single-arch laparoscopic and endoscopic cooperative surgery
Tumor recurrence rate
Time frame: 2 years
the operation time
Time frame: one hour-five hours
the all number of postoperative complications( frequency,reflux esophagitis and bile reflux gastritis)
Time frame: 2 years
Plan to share: Yes
No publications or documents are linked to this record.
This study is status unknown, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.
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Gastrointestinal Stromal Tumors→
First Affiliated Hospital Xi'an Jiaotong University