An interventional study of Deep neuromuscular blockade and Moderate neuromuscular blockade in General Anesthesia, sponsored by Yonsei University. Completed at 1 site in Korea, Republic of. Open to participants aged 19 Years to 80 Years. Per ClinicalTrials.gov, last updated 2017-12-18.
Sponsored by Yonsei University · Not applicable, Interventional, and Prevention
The purpose of this study is to investigate and compare the postoperative quality of recovery between the deep neuromuscular blockade and moderate neuromuscular blockade during robotic gastrectomy.
Yonsei University is the lead sponsor of 1,387 studies on the registry; 232 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Rocuronium will be administered continuously to achieve post-tetanic count 1-2 during surgery.
Drug: Deep neuromuscular blockade
Rocuronium will be administered continuously to achieve Train-of-four 1-2 during surgery.
Drug: Moderate neuromuscular blockade
neuromuscular blockade will be performed using a continuous infusion of rocuronium. Post-tetanic count 1-2 will be maintained during surgery. After the end of surgery, sugammadex of 4 mg/kg will be administered to reverse neuromuscular blockade.
neuromuscular blockade will be performed using a continuous infusion of rocuronium. Train-of-four 1-2 will be maintained during surgery. After the end of surgery, sugammadex of 2 mg/kg will be administered to reverse neuromuscular blockade.
Postoperative quality of recovery
The postoperative quality of recovery will be evaluated at 24 and 48 hours after the end of surgery by the investigator who are blinded to the group assignments.
Time frame: within 48 hours after the end of surgery.
Surgical condition
Surgical condition will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.
Time frame: within 48 hours after the end of surgery
shoulder pain
shoulder pain will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.
Time frame: within 48 hours after the end of surgery
abdominal pain
abdominal pain will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.
Time frame: within 48 hours after the end of surgery
nausea and vomiting
nausea and vomiting will be evaluated after the end of surgery by the investigator who are blinded to the group assignments.
Time frame: within 48 hours after the end of surgery
Plan to share: No — no plan to share data
No publications or documents are linked to this record.
This study is completed, as verified in Dec 2017. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Yonsei University