An observational study in Neoplasms, sponsored by Southern Medical University, China. Status unknown at 1 site in China. Per ClinicalTrials.gov, last updated 2018-10-12.
Sponsored by Southern Medical University, China · Observational
Previously published studies have indicated that there exist difference in electrical properties (EPs), i.e., the conductivity and relative permittivity, between malignant and adjacent normal tissue, which will be useful in the early detection of cancers. However the EP information mainly based on ex vivo measurement of cancer tissues, and few data in vivo were published. The purpose of this study is to in vivo measure the electrical properties of the malignant tissues.
The measurements were safety guaranteed and were conducted during the cancer surgeries. Before the tissue was excised from the patient,the pathologist assisted the operator (already at the operating room) responsible for the measurement.The measurement of malignant and corresponding normal tissues were both performed. The tissues for dielectric properties measurement were classified as normal or malignant by the pathologist based on his own expertise and decision criteria (visual inspection, anatomy) and the per-operative histological examination. The measurements were directly performed on the tissue before excision.The sites of the measured malignant tissues were marked,doubletracked according to the pathological report to make sure the marked sites are malignant. The patient age and tissue temperature at the time of measurement were recorded.
Southern Medical University, China is the lead sponsor of 31 studies on the registry; 6 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The patients who are diagnosed with cancer disease and about to have an operation to excise the cancer tissues.
Exclusion Criteria:
The dielectric properties of the tissues were measured using the open-ended coaxial line method. The measurement system consisted of a network analyzer (Model 4395A, Agilent Corp., Santa Clara, CA) associated with an S-parameter test set (Model 87511A, Agilent Corp., Santa Clara, CA). A semi-rigid coaxial line with a diameter of 3.58 mm was connected to the network analyzer system by using a Bayonet Neill-Concelman connector. The other tip of the coaxial line (probe) was placed on the flat bare surface of the tissue.
Conductivity of the Malignant Tissues measured In Vivo
Time frame: one year
Relative Permittivity of the Malignant Tissues measured In Vivo
Time frame: one year
Plan to share: Undecided
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Southern Medical University, China