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CompletedNCT02733237Updated Mar 6, 2017

Oxytocin Effects on the Tolerance of Infidelity

An interventional study of oxytocin treatment and placebo treatment in Healthy, sponsored by University of Electronic Science and Technology of China. Completed at 1 site in China. Open to participants aged 19 Years to 28 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-03-06.

Sponsored by University of Electronic Science and Technology of China · Not applicable, Interventional, and Basic science

From the registry’s dates

  • Registered 11 months after the study started (first participant enrolled Apr 2015, registered Mar 2016).
Phase
Not applicable
Study type
Interventional
Enrollment
160
Allocation
Randomized
Ages
19 Years to 28 Years
Sex
All
01

Study summary

To investigate whether intranasal oxytocin (40 IU) treatment can influence the tolerance of infidelity in males and females.

Read the detailed description

In a double-blind, between-subject, placebo controlled design, investigators plan to investigate the effect of oxytocin treatment on the tolerance of infidelity. Male and female subjects would firstly see a neutral face of the opposite sex presented with a sentence descried their fidelity or infidelity behavior (sexual or emotional) in a relationship. Next the participant will rate the attractiveness, likability and trustworthiness of each individual, and whether they would like to have a short/long relationship with him/her. After that there will be some implicit attitude tasks to test their implicit attitude towards potential partners exhibiting previous fidelity or and infidelity.

02

Conditions studied

  • Healthy

Keywords

  • oxytocin
  • infidelity
03

In context

Lead sponsor

University of Electronic Science and Technology of China is the lead sponsor of 109 studies on the registry; 35 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
19 Years to 28 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Healthy subjects without past or current psychiatric or neurological disorders

Exclusion criteria

Exclusion Criteria:

  • history of head injury;
  • pregnant,menstruating,taking oral contraceptives
  • medical or psychiatric illness.
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Investigator)
Enrollment
160 participants (actual)

Study arms

  • Experimental
    male oxytocin group

    male subjects with oxytocin treatment

    Drug: oxytocin treatment

  • Experimental
    female oxytocin group

    female subjects with oxytocin treatment

    Drug: oxytocin treatment

  • Placebo comparator
    male placebo group

    male subjects with placebo treatment

    Drug: placebo treatment

  • Placebo comparator
    female placebo group

    female subjects with placebo treatment

    Drug: placebo treatment

Interventions

  • Drugoxytocin treatment

    intranasal administration of oxytocin (40 IU)

  • Drugplacebo treatment

    intranasal administration of placebo (40 IU)

06

What researchers measure

Primary outcomes

  1. attitude towards fidelity and infidelity of potential mate.

    attitude is measured by the rating scores for likability, attractiveness and trustworthiness

    Time frame: 1 hour

07

Study locations

1 site
  • China, Sichuan
    Chengdu, Sichuan 611731, China
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 6, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02733237
Lead sponsor
University of Electronic Science and Technology of China
Responsible party
Keith Kendrick (Professor, University of Electronic Science and Technology of China) — Principal investigator
First posted
Apr 11, 2016
Start date
Apr 2015
Primary completion
Apr 2016
Completion
May 2016
Last update
Mar 6, 2017

Study contacts

Keith Kendrick, Dr.
principal investigator · University of Electronic Science and Technology of China
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2017. You cannot join it, but the record below documents what was studied.

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