An interventional study of Training Group and Control Group in Bronchiectasis, sponsored by University of Nove de Julho. Completed at 1 site in Brazil. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2019-08-16.
Sponsored by University of Nove de Julho · Not applicable, Interventional, and Treatment
This study will investigate the short-and long-term effects of the home-based pulmonary rehabilitation on peripheral muscle strength, functional capacity and quality of life in patients with bronchiectasis. The participants will be randomized into two groups: control group (usual care and recommendations for practice exercise) and training group, that will perform aerobic (stepping training) and resistance training (lower and upper limbs) for eight weeks, three times a week. At baseline, immediately after finishing and after six months the patients will undergo assessments.
Home-based pulmonary rehabilitation (HBPR) has been used in patients with chronic obstructive pulmonary disease, asthma and pulmonary fibrosis. Results from HBPR have been similar to those observe in the outpatient pulmonary rehabilitation such improvement in exercise capacity, symptoms and quality of life. However, HBPR has not yet been investigated in patients with bronchiectasis, a progressive and debilitating disease with a high socioeconomic impact. Objective: To investigate the short-and long-term effects of the home rehabilitation program in peripheral muscle strength, functional capacity and quality of life in patients with bronchiectasis. Methods: Patients diagnosed with bronchiectasis will be recruited from the Obstructive Diseases Outpatient Clinic of the Hospital das Clínicas - Medicine School, University of São Paulo. Participants will be randomized into two groups: control group (usual care and recommendations for performing exercises and respiratory physiotherapy) and training group, that will perform aerobic (stepping training) and resistance training (lower and upper limbs) for eight weeks, three times a week. All patients will receive a phone call once a week and patients allocated to the training group, additionally, will get a home visit every 15 days. At baseline, immediately after finishing and after six months of the HBPR patients will undergo to assessments. Expected results: HBPR will have positive effects on exercise tolerance and quality of life. Also, this study will contribute to future guidelines on the recommendation of HBPR for patients with bronchiectasis.
368 studies on the registry are indexed under Bronchiectasis; 104 are open to participants now.
This study's enrollment of 66 is close to the median of 60 across 233 interventional studies indexed under Bronchiectasis.
Browse Bronchiectasis studies →University of Nove de Julho is the lead sponsor of 239 studies on the registry; 51 are open to participants now.
Of its 8 completed or terminated interventional studies of FDA-regulated products, 1 (13%) have results posted.
Counted across the registry records on this site, refreshed daily.
Clinical diagnosis and/or tomographic bronchiectasis Clinically stable (no change in symptoms of dyspnea, in the amount and color of the secretion) Have completed the outpatient pulmonary rehabilitation for more than a year Not engaged in a regular physical activity.
Exclusion Criteria:
Smokers With other lung related diseases (asthma, COPD and cystic fibrosis) Severe cardiovascular diseases Musculoskeletal limitation Unable to perform the tests and the training protocol due desaturation (pulse oxygen saturation ≤ 80%) over the recommended exercise intensity.
Patients with bronchiectasis in home-based pulmonary rehabilitation
Other: Training Group
Patients with bronchiectasis in usual care and recommendations for performing exercises
Other: Control Group
Three sessions per week, each lasting 50 minutes, during eight weeks. * Aerobic training in stepping training. * Resistance training: Three sets of eight repetitions each, in both simultaneous members, using an elastic band. The trained muscles are quadriceps, hamstrings, deltoid and biceps. * Once a week, patients will receive a phone call and every two weeks, patients will get a visit of the researcher at his home.
Also known as: Physical training intervention
* The participants will receive verbal and written information about the importance of physical activity and walk in moderate intensity, at least, three times a week for 30 minutes. * Participants will not receive any supervised physical training. * Once a week, patients will receive a phone call to provide support and general advice.
Also known as: Physical activity intervention
Distance, in meters, performed in the Incremental Shuttle Walk Test
Measurement of functional capacity and exercise tolerance
Time frame: up to 9 months
Time, in seconds, performed in the Endurance Shuttle Walk Test
Measurement of functional capacity and exercise tolerance
Time frame: up to 9 monthsst
Number of steps performed in the Incremental Step Test
Measurement of functional capacity and exercise tolerance
Time frame: up to 9 months
Physical functioning domain scale in the Quality of Life Questionnaire-Bronchiectasis (QoL-B)
Quality of Life Questionnaire
Time frame: up to 9 months
Kilogram-force (kgf) of quadriceps femoris
Peripheral Muscle Strength
Time frame: up to 9 months
Number of steps per day, measured by a pedometer
Physical activity in daily life
Time frame: up to 9 months
Plan to share: No
This study is completed, as verified in Aug 2019. You cannot join it, but the record below documents what was studied.
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University of Nove de Julho